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A Pholidota chinensis-derived dihydrophenanthrene acts as a bioactive constituent to trigger GPx4-mediated ferroptosis in colorectal cancer

Bibliographic Data

ID21544058
AuthorsTing-I Kao, Ting‐I Kao (Chang Gung University), Sio-Hong Lam (National Cheng Kung University), Shun-Hua Chen (0000-0002-6158-5829), Shun‐Hua Chen (0000-0002-4585-9279, National Chi Nan University, corresponding author), Sheng-Chieh Tsai (Kaohsiung Medical University), Chien-Hsing Lee, Chien‐Hsing Lee (0000-0002-0576-7150, Kaohsiung Medical University), Hung-Te Hsu, Hung‐Te Hsu (0000-0002-2140-3146, Kaohsiung Medical University), Yun-Cian Huang (Kaohsiung Medical University), Yu-Li Chen (0000-0002-5282-6088), YR Chen (Chang Gung University of Science and Technology, corresponding author), Chun‐Hong Chen (0000-0002-3028-5508, Kaohsiung Medical University, corresponding author), Chun-Hong Chen, Po-Jen Chen (0000-0002-0135-8798, Kaohsiung Medical University, corresponding author)
Year2026
Volume371
Pages122154
Publication date2026-12-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.122154
PMID42398657
OpenAlexW7167365993
LanguageEN
References cited52

Bioactive compound · Biological activity · Cell culture · Cytotoxicity · In silico · Zebrafish · Andrographolide Research and Applications · Ferroptosis and cancer prognosis · Phytochemistry and biological activities of Ficus species

  • Ferroptosis

    Open Access•Scott J Dixon, Kathryn M Lemberg et al.•Cell•2012

  • Pholidota Chinensis Alleviates Azoxymethane/Dextran Sulfate Sodium-Induced Colorectal Carcinogenesis Through Inhibition of Tlr4 and Cox-2

    Open Access•Lilong Liu, Li-Long Liu et al.•African Journal of Traditional…•2015

  • Pholidota chinensis Lindl alleviates diabetic kidney disease by restoring mitochondrial dynamics and promoting mitophagy

    Open Access•Chenhui Xia, Huixi Chen et al.•Journal of Ethnopharmacology•2026

Highly citedNo

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