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The trajectory of anxiety and depression in people presenting to a cardiac inherited disease service

A longitudinal study

Bibliographic Data

ID21580004
AuthorsClaire O’Donovan (0000-0002-6272-7606, University of Auckland), Claire E O’Donovan (Department of Psychological Medicine, The University of Auckland, Auckland, New Zealand), J R Skinner (0000-0002-3653-0412, University of Auckland), Edward Broadbent (0000-0003-3626-9100, Department of Psychological Medicine, The University of Auckland, Auckland, New Zealand, corresponding author)
Year2021
Volume36
Issue10
Pages1260-1274
Publication date2021-10-03
Open AccessNo
TypeARTICLE
VenuePsychology & Health (JOURNAL)
Journal identifiersISSN: 0887-0446 • E-ISSN: 1476-8321
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/08870446.2020.1836181
PMID33090029
OpenAlexW3093773588
LanguageEN
References cited23

Objective Little is known about the psychological experiences of individuals being investigated for cardiac inherited diseases (CID). This study aimed to assess the prevalence, trajectory and associated variables of anxiety and depression in this population.Design This was a longitudinal study with 116 individuals being investigated for a CID; 85 (73%) completed follow-up.Main Outcome Measures Questionnaires were administered at the first appointment, post-disclosure of genetic results, and six-months later. Questionnaires measured demographic and psychological variables. The NZCID Registry provided clinical and genetic information.Results Thirty-seven (43%) individuals reported clinical and subclinical levels of anxiety and/or depression at least once. Anxiety and depression at follow up were associated with anxiety (p < .001) and depression (p < .001) at baseline. Elevated anxiety and depression scores at any point were also associated with more reporting of somatic symptoms (p < .001), poorer social support (p < .01) and greater intolerance for uncertainty (p < .001). There were five different trajectories of anxiety and depression: stable-low, stable-high, increasing, decreasing and fluctuating.Conclusion A significant minority of individuals being investigated for a CID experience anxiety and depression. Ongoing screening for anxiety, depression, social support and somatic symptoms could help identify those individuals

Anxiety · Disease · Economics · Keynesian economics · Longitudinal study · Pathology · Physics · Psychiatry · Trajectory · BRCA gene mutations in cancer · Cardiac electrophysiology and arrhythmias · Clinical Psychology · Medicine · Psychology · Psychosomatic Disorders and Their Treatments · Internal Medicine

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