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Initial evidence for a culturally adapted opioid overdose harm reduction intervention

Bibliographic Data

ID21605046
AuthorsBrittany D Miller-Roenigk (0000-0003-2001-7187, University of Kentucky, corresponding author), Paris B Wheeler (0000-0003-3551-5197, University of Cincinnati)
Year2026
Pages1-11
Publication date2026-05-17
Open AccessNo
TypeARTICLE
VenueDrugs Education Prevention and Policy (JOURNAL)
Journal identifiersISSN: 0968-7637 • E-ISSN: 1465-3370
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09687637.2026.2673074
OpenAlexW7161484466
LanguageEN
References cited36

Background Rates of opioid overdose continues to rise among Black adults, despite decreases in overdose among other racial and ethnic groups in the U.S. Opioid overdose among Black populations can be attributed to both intentional and unintentional opioid analogues (e.g., fentanyl) use and contamination of other drugs, such as stimulants. Opioid overdose among Black adults is seen at disproportional rates in the Midwest, such as in Kentucky and Ohio. Despite these risks, research examining harm reduction preventions and interventions among Black adults who report nonmedical use of opioids and increasingly dangerous stimulants has been vastly understudied.Method The current study adapts and tests a one-time, educational harm reduction intervention—which includes naloxone and fentanyl test strip (FTS) distribution—that is community-engaged and culturally informed. The intervention was pilot tested (clinical trial NCT06609278) among a sample of n = 57 Black adults in Louisville, KY and Cincinnati, OH. Eligible participants included men and women aged 18-65, reporting nonmedical opioid and/or stimulant use in the past six months.Results Results indicate preliminary evidence of efficacy of the intervention and the opioid overdose harm reduction strategies presented.Conclusions Initial findings of this study have important implications for harm reduction strategies to prevent and reverse opioid-related overdoses among Black adults

Drug overdose · Harm · Harm reduction · Opioid · Opioid abuse · Opioid overdose · HIV, Drug Use, Sexual Risk · Opioid Use Disorder Treatment · Substance Abuse Treatment and Outcomes

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Highly citedNo

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