Lack of Premeditation Predicts Aberrant Behaviors Related to Prescription Opioids in Patients with Chronic Pain

A Cross-Sectional Study

Bibliographic Data

ID21645110
AuthorsGabrielle Hettie (Department Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA), Chinwe Nwaneshiudu (Department Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA), Chinwe A Nwaneshiudu (0000-0001-8792-0886, Stanford University), Maisa S Ziadni (0000-0001-8371-0646, Department Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA), Beth D Darnall (0000-0003-3590-511X, Department Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA), Sean Mackey (0000-0001-7744-5348, Department Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA), Dokyoung S You (0000-0003-0724-7324, Department Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA, corresponding author)
Year2021
Volume56
Issue12
Pages1904-1909
Publication date2021-10-15
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueSubstance Use & Misuse (JOURNAL)
Journal identifiersISSN: 1082-6084 • E-ISSN: 1532-2491
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/10826084.2021.1958853
PMID34369839
OpenAlexW3190245044
LanguageEN
References cited33

OBJECTIVE: In light of the opioid epidemic, there is a need to identify factors that predict aberrant opioid behaviors including misuse and abuse. Impulsivity has been extensively studied in addiction literature, but not in the context of opioid misuse. Hence, this study aimed to identify which of the impulsivity facets (negative urgency, positive urgency, sensation seeking, lack of perseverance, and lack of premeditation) would predict current aberrant opioid-related behaviors in patients with chronic pain. METHODS: = 55 years), and White/Caucasian (84%). Upon consent, they completed a series of surveys including UPPS-P Impulsive Behavior Scale, the Current Opioid misuse Measure, Pain Catastrophizing Scale, PROMIS-anxiety, depression, and physical function, and a 0-10 numerical pain rating scale. Ordinal regression analyses were conducted to test study hypotheses. RESULTS: Contrary to expectations, only lack of premeditation predicted higher odds of aberrant opioid-related behaviors in the past 30 days, after controlling for known covariates, and explained 26% of variance. Interestingly, lack of premeditation together with pain catastrophizing as a covariate explained 56% of the variance in aberrant opioid-related behaviors. DISCUSSION: The current study is the first to identify a potential role of lack of premeditation as an impulsivity facet predicting aberrant opioid-related behaviors among patients with chronic pain

Addiction · Anxiety · Chronic pain · Cross-sectional study · Impulsivity · Opioid · Pain catastrophizing · Personality · Psychiatry · Sensation Seeking · Clinical Psychology · Eating Disorders and Behaviors · Medicine · Opioid Use Disorder Treatment · Psychology · Substance Abuse Treatment and Outcomes · Internal Medicine

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