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Motivations for Prescription Drug Misuse Related to Mental Health Problems in Adults

Bibliographic Data

ID21645568
AuthorsTess K Drazdowski (0000-0002-2339-0780, UCLA Integrated Substance Abuse Programs, Los Angeles, California, USA, corresponding author), Marya Schulte (UCLA Integrated Substance Abuse Programs, Los Angeles, California, USA), Marya T Schulte (0000-0002-3307-5637, OASIS Clinic), Kate Wolitzky‐Taylor (0000-0001-6199-4350, UCLA Integrated Substance Abuse Programs, Los Angeles, California, USA), Holle Schaper (Oregon Social Learning Center, Eugene, Oregon, USA), Jason E Chapman (0000-0002-9396-5877, Oregon Social Learning Center, Eugene, Oregon, USA)
Year2022
Volume57
Issue2
Pages316-327
Publication date2022-01-28
Open AccessNo
TypeARTICLE
VenueSubstance Use & Misuse (JOURNAL)
Journal identifiersISSN: 1082-6084 • E-ISSN: 1532-2491
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/10826084.2021.2012687
PMID34903123
OpenAlexW4200268530
LanguageEN
Citations received3
References cited33

BACKGROUND: Prescription drug misuse (PDM) is a significant public health problem associated with mental health symptoms. OBJECTIVES: This project investigates the connections between PDM motivations and mental health to inform intervention efforts. METHODS: = 128,205; 53% female) this project investigated which motivations for misuse are related to past-year mental health problems including any mental illness, serious mental illness, major depressive episode, and suicidal thoughts. Complex samples logistic regression models of the main motivation of PDM for each mental health problem were conducted separately for each prescription drug class (i.e., opioids, tranquilizers, sedatives, and stimulants) while controlling for demographic characteristics. RESULTS: Adults that reported PDM were more likely than those with no PDM to endorse past year mental health problems. Compared to those that reported PDM of other medications, those misusing prescription opioids and tranquilizers to help with emotions and misusing sedatives to "relax or relieve tension" were more likely to have all categories of mental health problems. Those that misused prescription stimulants to "help study" had lower odds of all mental health problems. CONCLUSIONS: While there were differences based on prescription drug class, a range of motivations increased adults' likelihood to have mental health problems and common themes were found across drug classes. While causality is still undetermined, prevention and intervention efforts that are multifaceted and individualized, while broadly providing adults with other ways to cope with negative emotions are likely to help reduce PDM

Logistic regression · Medical emergency · Medical prescription · Mental health · Mental illness · Occupational safety and health · Odds · Opioid · Poison control · Prescription Drug Misuse · Psychiatry · Psychological intervention · Public health · Suicide prevention · Medicine · Neuroethics, Human Enhancement, Biomedical Innovations · Nursing · Opioid Use Disorder Treatment · Psychology · Substance Abuse Treatment and Outcomes

  • A New Scale for Assessing Benzodiazepine Use Motives Among Community and Clinical Samples

    Open Access•Lea Peter, Bence András Lázár et al.•International Journal of Mental…•2025

  • Associations Between Drug Use and Mental Health Service Utilization Among US Adults

    Open Access•Yu-Tien Chang, Yen-Han Lee•International Journal of Mental…•2023

  • Factors Influencing Drug and Substance Abuse among Secondary School Students in Zimbabwe

    Open Access•Chikuvadze Pinias, Saidi Enia•Mediterranean Journal of Social…•2023

  • Management of Chronic Insomnia Disorder in Adults

    Open Access•Amir Qaseem, Devan Kansagara et al.•Annals of Internal Medicine•2016

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    Bridget F Grant, Frederick S Stinson et al.•Archives of General Psychiatry•2004

  • Trends and Geographic Patterns in Drug and Synthetic Opioid Overdose Deaths — United States, 2013–2019

    Open Access•Christine L Mattson, Lauren J Tanz et al.•MMWR. Surveillance Summaries•2021

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Citations per year1
Citation span2023 - 2025 (3)
Highly citedNo

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