Cannabis Use is an Independent Risk Factor for Manic Episode
A Report from 380,265 Bipolar Inpatients
Bibliographic Data
| ID | 21645690 |
|---|---|
| Authors | Rikinkumar S Patel (0000-0002-2895-9155, Department of Psychiatry, corresponding author), Zainab Cheema (Department of Psychiatry), Ashima Singla (Department of Psychiatry), Miglia Cornejo (School of Osteopathic Medicine, Arizona, A.T. Still University, Mesa, Arizona, USA), Geetika Verma (0000-0001-5401-9821, Department of Psychiatry) |
| Year | 2022 |
| Volume | 57 |
| Issue | 3 |
| Pages | 344-349 |
| Publication date | 2022-02-23 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Substance Use & Misuse (JOURNAL) |
| Journal identifiers | ISSN: 1082-6084 • E-ISSN: 1532-2491 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/10826084.2021.2012690 |
| PMID | 34895014 |
| OpenAlex | W4200487393 |
| Language | EN |
| Citations received | 3 |
| References cited | 24 |
OBJECTIVES: To evaluate the odds for bipolar disorder (BP) mania and depression-related hospitalization due to cannabis use disorders (CUD). METHODS: We conducted a cross-sectional study using the national inpatient sample (NIS), and included adult BP hospitalizations sub-grouped by manic (N = 209,785) versus depressive episodes (N = 170480). A logistic regression model was used to evaluate adjusted odds ratio (aOR) of association between CUD and BP-mania-related hospitalizations and was adjusted for demographics confounders, psychiatric comorbidities and other substance use disorders (SUD). RESULTS: Comorbidities were less prevalent in BP mania compared to BP depression: anxiety disorders (22.7% vs. 35.3%), PTSD (8.7% vs. 14.3%), and personality disorders (15.4% vs. 20.5%). Among SUD, methamphetamine (aOR 1.27, 95%CI 1.22 - 1.32) and CUD (aOR 1.53, 95%CI 1.50 - 1.56) had increased odds for hospitalization for BP mania. CONCLUSION: CUD increases the odds for hospitalization for BP manic episode by 53%. Due to the rising prevalence of cannabis use among patients with BP it is important to provide substance use counseling/psychoeducation and discourage cannabis use among youth to prevent long-term adverse consequences
Anxiety · Bipolar disorder · Bipolar I disorder · Cannabis · Cross-sectional study · Mania · Mood · Odds ratio · Psychiatry · Psychoeducation · Psychological intervention · Bipolar Disorder and Treatment · Cannabis and Cannabinoid Research · Medicine · Substance Abuse Treatment and Outcomes · Internal Medicine
| Citations per year | 0.75 |
|---|---|
| Citation span | 2022 - 2024 (3) |
| Highly cited | No |