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Cocaine-Related Suicide Attempts in Rio Grande Do Sul, Brazil

Toxicological Profile and Temporal Analyses

Bibliographic Data

ID21645857
AuthorsBruno Pereira dos Santos (0000-0002-7624-5966, Faculty of Pharmacy, Federal University of Rio Grande do Sul (UFRGS), corresponding author), Viviane Cristina Sebben (0000-0001-9388-4105, Toxicological Information Center of Rio Grande do Sul (CIT-RS)), Marcelo Dutra Arbo (0000-0002-0434-1553, Faculty of Pharmacy, Federal University of Rio Grande do Sul (UFRGS))
Year2026
Pages1-7
Publication date2026-05-11
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueSubstance Use & Misuse (JOURNAL)
Journal identifiersISSN: 1082-6084 • E-ISSN: 1532-2491
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/10826084.2026.2670601
PMID42116663
OpenAlexW7160891801
LanguageEN
References cited45

BACKGROUND: Poisoning is a common method for suicide or suicide attempts. In this context, drug use, including cocaine, is described as a risk factor. Therefore, the use of cocaine in suicide attempts by self-poisoning should be investigated. METHODS: Data from poisoning cases registered by a Brazilian Poison Center between 2005 and 2024 were collected. Only suicide attempt cases involving cocaine as a toxic agent were selected. Demographic and toxicological variables were analyzed. Temporal analysis was carried out to verify changes along the analyzed period. RESULTS: A total of 1,089 cases of cocaine-related suicide attempts were registered. Approximately 64.1% were males, and young adults (20-39 years old) were the most prevalent age group (73.7%). An ARIMA model indicated that the number of observed cases from 2020 onwards was higher than expected, considering data up to 2019. An increase of 1,833% in cocaine-related suicide attempts over a 20-year period was assessed. CONCLUSIONS: This study identified a marked rise in cocaine-related suicide attempts in recent years, with a clear shift during the COVID-19 pandemic. The predominant profile is men aged 20-39 years

Injury prevention · Occupational safety and health · Poison control · Suicide attempt · Suicide methods · Suicide prevention · Forensic Toxicology and Drug Analysis · Human Factors and Ergonomics · Poisoning and overdose treatments · Suicide and Self-Harm Studies

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