Concurrent Polysubstance Use Profiles in Young Nightlife Attendees in Argentina
Harm Reduction Strategies and Their Impact on Negative Consequences
Bibliographic Data
| ID | 21645936 |
|---|---|
| Authors | Emilia Musso (0000-0002-4204-4496, Instituto de Investigaciones Psicológicas, corresponding author), Belén Del Valle Vera (0000-0002-7840-9493, Instituto de Investigaciones Psicológicas), Florencia Caneto (0000-0001-9249-6573, Instituto de Investigaciones Psicológicas), Juan Carlos Godoy (0000-0002-1622-1647, Instituto de Investigaciones Psicológicas), Fermín Fernández Calderón (0000-0002-2981-1670, Universidad de Huelva) |
| Year | 2026 |
| Volume | 61 |
| Issue | 10 |
| Pages | 1581-1592 |
| Publication date | 2026-08-24 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Substance Use & Misuse (JOURNAL) |
| Journal identifiers | ISSN: 1082-6084 • E-ISSN: 1532-2491 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/10826084.2026.2613715 |
| PMID | 41766088 |
| OpenAlex | W7133227323 |
| Language | EN |
| References cited | 67 |
BACKGROUND: Polysubstance use is common in nightlife settings and has been linked to a variety of negative outcomes. Harm reduction strategies (HRS), which aim to reduce harms, may differ across consumption patterns. This paper identifies polysubstance use classes among young attendees of recreational settings, examines their HRS use, and explores associations with negative outcomes by use pattern. METHODS: 596 Argentinean polysubstance users aged 18-35 who attended recreational settings completed a survey assessing substance use, HRS use, and consequences experienced. Latent Class Analysis identified polysubstance use patterns. Hierarchical multiple regression was used to assess associations between HRS use and the experimentation of negative consequences within classes. RESULTS: Three classes of concurrent polysubstance use were identified: Low, Moderate, and Severe. Participants in the Moderate and Severe Polysubstance Use classes employed a greater number of HRS but also experienced psychological and social negative consequences more frequently. Within the different polysubstance use classes, significant association between the use of certain harm reduction strategies and a lower likelihood of reporting substance-related harms was found. CONCLUSIONS: Our study enhances understanding of the relationship between HRS and substance-related consequences across polysubstance use profiles. This should inform harm reduction messages for young people who use multiple drugs
Harm · Harm reduction · Nightlife · Polysubstance dependence · Forensic Toxicology and Drug Analysis · Homelessness and Social Issues · Substance Abuse Treatment and Outcomes
Simultaneous Versus Concurrent Use of Alcohol and Cannabis in the National Alcohol Survey
Use of alcohol protective behavioral strategies among college students
Polysubstance use
The new life stage of emerging adulthood at ages 18–29 years
Ten frequently asked questions about latent class analysis.
Harm Reduction Strategies and Drug-Related Negative Consequences in the Dance Music Scene
Patterns of Substance Use Across the First Year of College and Associated Risk Factors
Illicit Drug Use and Associated Problems in the Nightlife Scene
Co-Use of Alcohol and Cannabis
Is the Sum Greater than its Parts? Variations in Substance-Related Consequences by Conjoint Alcohol-Marijuana Use Patterns
Drug Use and Meanings of Risk and Pleasure
Harm Reduction From Below
Latent Class Analysis
| Citation velocity | historical |
|---|---|
| Highly cited | No |