Nicotine Dependence and Its Impact on Poly-Tobacco Use Among US Adults
Bibliographic Data
| ID | 21646244 |
|---|---|
| Authors | Ximeng Zhao (0000-0002-0016-2603, Florida International University, corresponding author), Wei Li (0000-0002-3581-849X, Yale University), Olatokunbo Osibogun (0000-0001-8902-4356, Florida International University) |
| Year | 2026 |
| Volume | 61 |
| Issue | 1 |
| Pages | 61-68 |
| Publication date | 2026-01-02 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Substance Use & Misuse (JOURNAL) |
| Journal identifiers | ISSN: 1082-6084 • E-ISSN: 1532-2491 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/10826084.2025.2544302 |
| PMID | 40836387 |
| OpenAlex | W4413367372 |
| Language | EN |
| Citations received | 1 |
| References cited | 34 |
BACKGROUND: Poly-tobacco use (PTU), the consumption of multiple tobacco products, is linked to higher mortality rates compared to single product use. Existing cross-sectional studies have demonstrated a relationship between PTU and nicotine dependence (ND). This study explores whether higher levels of ND increase the risk of transitioning to PTU using a longitudinal cohort. METHODS: We utilized data from waves 1-6 (2013-2021) of the Population Assessment of Tobacco and Health study adult data. A standardized ND score, calculated from 16 items, was assigned to each participant at baseline. ND was treated as a continuous variable ranging from 1 (least dependent) to 5 (most dependent). Participants who were single product users at Wave 1 and had no prior history of PTU were included and followed through Waves 2-6. Any transition to PTU was defined as a case. Cox proportional hazard regression was used to assess the risk of transitioning to PTU, adjusting for potential confounders. RESULTS: A one-unit increase in ND was associated with a 41% increased risk of transitioning to PTU (aHR =1.411, 95% CI: [1.245, 1.599]). Younger age, family below poverty level, and substance use were also associated with increased risks of transitioning to PTU. CONCLUSIONS: These findings underscore the importance of ND as a key factor in the progression to PTU. Interventions targeting individuals with high ND levels may be effective in preventing the transition to PTU
Environmental health · Nicotine · Nicotine dependence · Population · Psychiatry · Tobacco use · Alcohol Consumption and Health Effects · Medicine · Psychology · Smoking Behavior and Cessation · Substance Abuse Treatment and Outcomes
Tobacco Product Use Among Adults – United States, 2021
Nicotine Addiction
Cross-Sectional Associations of Multiple Tobacco Product Use with Depressive and Anxiety Symptoms among Young Adult E-Cigarette Users
Nicotine Dependence and Factors Related to Smoking Cessation among Physicians in Estonia
Socioeconomic variations in nicotine dependence, self-efficacy, and intention to quit across four countries
Design and methods of the Population Assessment of Tobacco and Health (Path) Study
| Citations per year | 1 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |