The Association Between Drug Craving and Suicidal Thoughts and Behavior in Chinese Male Methamphetamine Inpatients
The Mediating Effect of Depressive Symptoms
Bibliographic Data
| ID | 21646597 |
|---|---|
| Authors | Xinyue Zhang (0009-0009-4555-8650, Tsinghua University, corresponding author), Arsalan Haider (0000-0002-0946-4624, Chinese Academy of Sciences), Yang Tian (0000-0001-6407-5608, Chinese Academy of Sciences), Linjun Jiang (Chinese Academy of Sciences), Dongmei Wang (0000-0001-6900-8295, Chinese Academy of Sciences, corresponding author), Xiang-Yang Zhang (Tsinghua University) |
| Year | 2026 |
| Pages | 1-8 |
| Publication date | 2026-03-26 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Substance Use & Misuse (JOURNAL) |
| Journal identifiers | ISSN: 1082-6084 • E-ISSN: 1532-2491 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/10826084.2026.2647132 |
| PMID | 41889193 |
| OpenAlex | W7141393923 |
| Language | EN |
| References cited | 30 |
BACKGROUND: Suicidal thoughts and behavior (STBs) are prevalent in patients with methamphetamine use disorder (MAUD). The present study aimed to examine the relationship between drug craving and STBs among Chinese MAUD inpatients, specifically focusing on the potential mediating role of depressive symptoms. METHODS: After quality control, 538 inpatients with MAUD were included in the study. Inpatients were recruited from a drug rehabilitation center. Data were collected using the Desires for Drug Questionnaire (DDQ), the Beck Depression Inventory (BDI), and the STBs question. RESULTS: Among MAUD inpatients, 7.6% exhibited STBs. Compared to those without STBs, patients with STBs had higher depressive symptoms scores, higher DDQ-negative reinforcement scores, and higher total DDQ scores. Significant positive associations were found among DDQ scores, depressive symptoms, and STBs. Mediation analysis indicated that the mediation effect of depressive symptoms was significant (mediation effect: 26%). CONCLUSION: Depressive symptoms serve as a mediator in the relationship between drug craving and STBs in MAUD inpatients. These findings highlight the necessity of incorporating depressive symptoms screening and intervention into addiction treatment which may be related to a lower prevalence of suicide risk
Addiction · Craving · Depressive symptoms · Drug · Methamphetamine · Neurotransmitter Receptor Influence on Behavior · Substance Abuse Treatment and Outcomes · Suicide and Self-Harm Studies
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| Highly cited | No |
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