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Osteoporosis and risk of fracture

Reference class problems are real

Bibliographic Data

ID21702249
AuthorsNicholas Binney (0000-0003-0686-3184, Erasmus MC, corresponding author)
Year2022
Volume43
Issue5-6
Pages375-400
Publication date2022-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueMetamedicine (JOURNAL)
Journal identifiersISSN: 0166-2031 • E-ISSN: 1573-1200
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s11017-022-09590-3
PMID36114828
OpenAlexW4296157603
LanguageEN
Citations received1
References cited43

Elselijn Kingma argues that Christopher Boorse’s biostatistical theory does not show how the reference classes it uses—namely, age groups of a sex of a species—are objective and naturalistic. Boorse has replied that this objection is of no concern, because there are no examples of clinicians’ choosing to use reference classes other than the ones he suggests. Boorse argues that clinicians use the reference classes they do because these reflect the natural classes of organisms to which their patients belong. Drawing on a thorough exploration of how the disease osteoporosis is defined in adults, I argue that clinicians do indeed make choices about which reference classes to use in diagnosis. Clinicians use young adult reference classes to diagnose osteoporosis in elderly patients. They also use young female reference classes to diagnose osteoporosis in elderly males. Clinicians adjust their reference classes so that the diagnosis of osteoporosis reflects a person’s risk of sustaining a fragility fracture. The ethical intuition that people with the same risk of fracture should receive the same diagnosis overwhelms the naturalistic intuition that reference classes should reflect natural classes of organisms of uniform functional design. Clinicians construct a variety of reference class types, including pathological reference classes and epidemiological population-specific reference classes, to serve this ethical intuition. I show how clinicians use several reference classes at once so that they can more accurately predict risk of fracture. Ultimately, the reference classes chosen and used in medical practice are quite different from those proposed in naturalistic philosophy of medicine

Alternative medicine · Cognitive science · Intuition · Osteoporosis · Pathology · Philosophy of medicine · Clinical Reasoning and Diagnostic Skills · Historical and modern epidemiology studies · Medicine · Mental Health and Psychiatry · Psychology

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Unique citing works1
Citations per year0,33
Citation span2023 - 2023 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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