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Is the replication crisis a base-rate fallacy

Bibliographic Data

ID21702380
AuthorsBengt Autzen (0000-0001-5487-4764, University College Cork, corresponding author)
Year2021
Volume42
Issue5-6
Pages233-243
Publication date2021-12-01
Open AccessYes
TypeARTICLE
VenueMetamedicine (JOURNAL)
Journal identifiersISSN: 0166-2031 • E-ISSN: 1573-1200
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s11017-022-09561-8
PMID35220515
OpenAlexW4214624990
LanguageEN
Citations received1
References cited21

Is science in the midst of a crisis of replicability and false discoveries? In a recent article, Alexander Bird offers an explanation for the apparent lack of replicability in the biomedical sciences. Bird argues that the surprise at the failure to replicate biomedical research is a result of the fallacy of neglecting the base rate. The base-rate fallacy arises in situations in which one ignores the base rate—or prior probability—of an event when assessing the probability of this event in the light of some observed evidence. By extension, the replication crisis would result from ignoring the low prior probability of biomedical hypotheses. In this paper, my response to Bird’s claim is twofold. First, I show that the argument according to which the replication crisis is due to the low prior of biomedical hypotheses is incomplete. Second, I claim that a simple base-rate fallacy model does not account for some important methodological insights that have emerged in discussions of the replication crisis

Biology · Economics · Epistemology · Fallacy · Positive economics · Statistics · Surprise · Mathematics · Meta-analysis and systematic reviews · Philosophy · Philosophy and History of Science · Psychology · Social Psychology · Statistical Methods in Clinical Trials

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Citations per year0.2
Citation span2021 - 2021 (1)
Highly citedNo

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