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When Artificial Intelligence Enters the Research Process

Implications for Data Integrity in Human Participants Research

Bibliographic Data

ID21747839
AuthorsMelissa Singer Pressman (0000-0001-7414-8532, Grand Canyon University, corresponding author)
Year2026
Pages15562646261453181-15562646261453181
Publication date2026-05-20
Open AccessYes
TypeARTICLE
VenueJournal of Empirical Research on Human Research Ethics (JOURNAL)
Journal identifiersISSN: 1556-2646 • E-ISSN: 1556-2654
PublisherSAGE Publications (PUBLISHER • US)
DOI10.1177/15562646261453181
PMID42159493
OpenAlexW7161816685
LanguageEN
References cited19

The rapid integration of generative artificial intelligence (AI) into academic and professional workflows is reshaping human participants research. While prior discourse has focused largely on AI-assisted writing and analysis, less attention has been given to its influence on data generation and integrity. This invited commentary examines emerging risks associated with generative AI use by researchers and participants, including data fabrication and AI-mediated participant responses. These developments challenge foundational assumptions regarding data authenticity, measurement validity, and the evidentiary basis of research. Implications for research ethics oversight, particularly for institutional review boards and research ethics committees, are also explored, including the need to consider transparency, data provenance, and methodological accountability in AI-enabled research environments. Practical strategies are proposed to mitigate risks. Ultimately, human participants research will require a shift toward systems that balance trust-based models with structured verification mechanisms, alongside the development of clear institutional and international guidelines for responsible AI integration

Accountability · Big data · Data integrity · Generative grammar · Human research · Research ethics · Workflow · Artificial Intelligence in Healthcare and Education · Ethics and Social Impacts of AI · Explainable Artificial Intelligence (XAI

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