Relationship Between Esophageal Motility Disorders and Autonomic Nervous System in Diabetic Patients
Pilot North African Study
Bibliographic Data
| ID | 21748339 |
|---|---|
| Authors | Syrine Gallas (0000-0001-7315-5773, University of Monastir), Gallas Syrine (University of Monastir), Maatallah Kanzali Mariem (University of Sousse), Knaz Hend (University of Monastir), Hend Knaz (University of Monastir), Latiri Imed (0000-0002-6074-4736, Hôpital Farhat Hached, corresponding author) |
| Year | 2022 |
| Volume | 16 |
| Issue | 3 |
| Pages | 15579883221098588-15579883221098588 |
| Publication date | 2022-05-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Men s Health (JOURNAL) |
| Journal identifiers | ISSN: 1557-9883 • E-ISSN: 1557-9891 |
| Publisher | SAGE Publications (PUBLISHER • US) |
| DOI | 10.1177/15579883221098588 |
| PMID | 35562861 |
| OpenAlex | W4280509018 |
| Language | EN |
| References cited | 36 |
Little attention has been given to esophageal disorders in diabetes mellitus. Pathophysiology of esophageal motility disorders (EMD) in patients with diabetes mellitus is multifactorial. The aims of the present study were: (a) to evaluate the prevalence of EMD in patients with Type 2 diabetes mellitus and (b) to determine the relationship between EMD and autonomic neuropathy as assessed by heart rate variability (HRV). All the patients completed a questionnaire about diabetes characteristics and gastrointestinal symptoms. Conventional esophageal manometry was performed in all patients. HRV was measured in three different situations (Lying Position 1, standing position, and Lying Position 2). The temporal and frequency domain parameters were considered for analysis. The prevalence of EMD in our patients was 60.5% ( n = 23). Low score physical activity was significantly more frequent in patients with EMD ( p = .03). There was an increase in sympathetic activity represented by the low frequency (LF) parameter ( p = .027) in the presence of EMD. Whereas parasympathetic modulation of heart rate represented by the high frequency (HF) parameter ( p = .027) was declined in patients with EMD compared to those without. The LF/HF ratio was significantly higher ( p = .002) in patients with EMD. EMD were prevalent in diabetes mellitus and were associated to autonomic nervous system dysfunction predominantly at the parasympathetic component
Autonomic nervous system · Autonomic neuropathy · Blood pressure · Cardiology · Diabetes mellitus · Disease · Esophageal motility disorder · Heart rate · Heart rate variability · Pathophysiology · Reflux · Type 2 Diabetes Mellitus · Cardiovascular Syncope and Autonomic Disorders · Gastroesophageal reflux and treatments · Heart Rate Variability and Autonomic Control · Medicine · Endocrinology · Gastroenterology · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |