Effects of Varicocele Surgical Repair on Serum Hormone and Inhibin B Levels for Patients With Varicocele

A Systematic Review and Meta-Analysis

Bibliographic Data

ID21748702
AuthorsDaxue Tian (Department of Urology, Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China), Chenchen Yang (0000-0002-2597-5942, Tengzhou Central People's Hospital), Bing Xie (0000-0002-8408-7910, Department of Medical Engineering, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China), Haijuan Li (0000-0001-9852-9209, Department of Clinical Nutrition, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China), Jie Li (0000-0002-5131-4769, Department of Anesthesiology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China), Diandong Yang (0000-0002-7614-0590, Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China), Zaisheng Zhu (Department of Urology, Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China)
Year2023
Volume17
Issue5
Publication date2023-09-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Men s Health (JOURNAL)
Journal identifiersISSN: 1557-9883 • E-ISSN: 1557-9891
PublisherSAGE Publications (PUBLISHER • US)
DOI10.1177/15579883231199400
LanguageEN
References cited25

Varicocele surgical repair can improve the function of the testis for patients with varicocele. We carried out a systematic review and meta-analysis to assess the effects of varicocele surgical repair on serum hormones and inhibin B levels in patients with varicocele. A literature search was performed in August 2022, and no language or geographic region restrictions were applied. The search included the following databases: PubMed, Embase, and Medline. A literature review was performed to identify all published clinical trials assessing serum hormone and inhibin B levels before and after varicocele surgical repair. The reference lists of retrieved studies were also investigated. A systematic review and meta-analysis were conducted. Eight articles were selected from 162 articles, including 452 patients. The combined analysis showed that after surgical treatment, mean serum testosterone, inhibin B, and sperm concentration levels increased compared with preoperative levels ( p

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