A Systematic Review and Meta-Analysis of the Efficacy and Safety of Tamsulosin Plus Tadalafil Compared With Tamsulosin Alone in Treating Males With Lower Urinary Tract Symptoms Secondary to Benign Prostrate Hyperplasia
Bibliographic Data
| ID | 21748864 |
|---|---|
| Authors | Rui Zhou (0000-0003-2412-8634, Department of Urology, Sichuan Science City Hospital, MianYang, China), Xuanyan Che (Capital Medical University), Zhongbao Zhou (0000-0002-9810-8145, Capital Medical University), Yue Ma (0009-0009-8408-0231, Department of Urology, Sichuan Science City Hospital, MianYang, China) |
| Year | 2023 |
| Volume | 17 |
| Issue | 1 |
| Publication date | 2023-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Men s Health (JOURNAL) |
| Journal identifiers | ISSN: 1557-9883 • E-ISSN: 1557-9891 |
| Publisher | SAGE Publications (PUBLISHER • US) |
| DOI | 10.1177/15579883231155096 |
| Language | EN |
| References cited | 24 |
Lower urinary tract symptoms (LUTS) secondary to benign prostrate hyperplasia (BPH) are common geriatric diseases, and its incidence rises with age. The treatment of BPH and LUTS is becoming a burden for health care. The meta-analysis was performed to evaluate the efficacy and safety of combination therapy (tamsulosin plus tadalafil) compared with tamsulosin alone in treatment of males with LUTS/BPH. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses were utilized to conduct this study. There were several databases available for literature retrieval, including Medline, Embase, PubMed, Scopus, Web of Science databases, and Cochrane Controlled Trials Register. To improve the comprehensiveness of the search, related references were also searched. Finally, six randomized controlled trials including 441 patients were included. The combination therapy had significant improvements in total International Prostate Symptom Score ( p
| Citation velocity | historical |
|---|---|
| Highly cited | No |