Pattern, Clinical Characteristics, and Impact of Family History on Prostate-Specific Antigen in Prostate Cancer
A Multicenter Study
Bibliographic Data
| ID | 21748955 |
|---|---|
| Authors | Chinonyerem O Iheanacho (0000-0001-7690-9024, University of Calabar, corresponding author), Valentine Uche Odili (University of Benin), Glen E Enakirerhi (University of Calabar), Edoise M Isiwele (0000-0002-6358-0757, University of Calabar), Akanimo Essiet (University Of Calabar Teaching Hospital) |
| Year | 2024 |
| Volume | 18 |
| Issue | 4 |
| Pages | 15579883241264949-15579883241264949 |
| Publication date | 2024-07-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Men s Health (JOURNAL) |
| Journal identifiers | ISSN: 1557-9883 • E-ISSN: 1557-9891 |
| Publisher | SAGE Publications (PUBLISHER • US) |
| DOI | 10.1177/15579883241264949 |
| PMID | 39054776 |
| OpenAlex | W4401037372 |
| Language | EN |
| References cited | 23 |
Prostate cancer (PCa) is a major cause of illness and death in men of Sub-Sahara African origin. The study assessed the pattern of PCa, the effect of family history on PSA at diagnosis, and clinical characteristics of PCa in Nigeria. A cross-sectional survey of 200 participants was performed within a 12-month period in Nigeria. Data were collected through patients’ interview and hospital records and analyzed using SPSS version 25. Descriptive and inferential statistics were performed. P values 2 = 0.017; adjusted R 2 = 0.002; df = 3; F = 1.154; p = .329) at diagnosis. PCa mostly occurred in men within 60 to 70 years of age, and family history of cancer did not predict PSA at diagnosis. Patients presented to health facilities at advanced or metastatic stages. These findings highlight the need for policies and strategies that encourage early PCa screening
Cancer · Confidence interval · Family history · Gynecology · Lower urinary tract symptoms · Multivariate analysis · Prostate · Prostate cancer · Univariate analysis · Cervical Cancer and HPV Research · Medicine · Prostate Cancer Diagnosis and Treatment · Prostate Cancer Treatment and Research · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |