Toward Precision Characterization and Treatment of Psychopathology
A Path Forward and Integrative Framework of the Hierarchical Taxonomy of Psychopathology and the Research Domain Criteria
Bibliographic Data
| ID | 21786408 |
|---|---|
| Authors | Sarah L Hagerty (0000-0002-1082-5511, VA Palo Alto Health Care System, corresponding author) |
| Year | 2023 |
| Volume | 18 |
| Issue | 1 |
| Pages | 91-109 |
| Publication date | 2023-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Perspectives on Psychological Science (JOURNAL) |
| Journal identifiers | ISSN: 1745-6916 • E-ISSN: 1745-6924 |
| Publisher | SAGE Publications (PUBLISHER • US) |
| DOI | 10.1177/17456916221079597 |
| PMID | 35867337 |
| OpenAlex | W4286561956 |
| Language | EN |
| Citations received | 1 |
| References cited | 55 |
A critical mission of psychological science is to conduct research that ultimately improves the lives of individuals who experience psychopathology. One important aspect of accomplishing this mission is increasing the likelihood that treatments will work for each person. I contend that treatment prognosis can be improved by moving toward a precision-medicine model. I advance a principle-driven framework for working toward these objectives. First, I synthesize the Hierarchical Taxonomy of Psychopathology and the Research Domain Criteria and demonstrate how integrating these models facilitates precision characterization of psychopathology. Second, I outline and demonstrate a systematic process for approaching treatment selection by leveraging precisely characterized representations of psychopathology. Finally, I advocate the research and clinical applications of this framework. Although clinical and psychological scientists are conducting exciting, multidisciplinary, and methodologically rigorous research in their respective domains, the impact of these pursuits will be maximized in the context of a unifying theoretical framework that supports a clear guiding mission
Multidisciplinary approach · Psychopathology · Psychotherapist · Research Domain Criteria · Social science · Sociology · Clinical Psychology · Computer Science · Mental Health and Psychiatry · Mental Health Research Topics · Psychology · Treatment of Major Depression
Diagnostic and Statistical Manual of Mental Disorders
The Path to Personalized Medicine
A New Initiative on Precision Medicine
The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology
Toward the future of psychiatric diagnosis
Research Domain Criteria (RDoC)
The Nimh Research Domain Criteria (RDoC) Project
Why Don't Physicians Follow Clinical Practice Guidelines?
The Hierarchical Taxonomy of Psychopathology (HiTOP)
The distinction between symptoms and traits in the Hierarchical Taxonomy of Psychopathology (HiTOP)
| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |