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Modelling costs of community-based HIV self-testing programmes in Southern Africa at scale

An econometric cost function analysis across five countries

Bibliographic Data

ID21878529
AuthorsMarc d’Elbée (0000-0002-8827-019X, London School of Hygiene & Tropical Medicine, corresponding author), Gabriela B Gomez (0000-0002-7409-798X, London School of Hygiene & Tropical Medicine), Linda Alinafe Sande (0000-0002-4246-5338, University of Liverpool), Lawrence Mwenge (0000-0002-8588-8939, Zambart), Collin Mangenah (0000-0002-0733-0622, Centre for Sexual Health and HIV AIDS Research), Cheryl Johnson (0000-0001-5499-5523, World Health Organization), Graham Medley (0000-0002-0030-7278, London School of Hygiene & Tropical Medicine), Graham F Medley (London School of Hygiene & Tropical Medicine), Melissa Neuman (0000-0002-8870-6504, London School of Hygiene & Tropical Medicine), Karin Hatzold (0000-0002-5117-3732, Population Services International), Elizabeth L Corbett (0000-0002-3552-3181, University of Liverpool), Gesine Meyer‐Rath (0000-0003-0439-381X, Boston University), Gesine Meyer-Rath (Department of Internal Medicine, Health Economics and Epidemiology Research Office (HE2RO) – University of the Witwatersrand, Johannesburg, South Africa), Fern Terris-Prestholt (0000-0003-1693-5196, Joint United Nations Programme on HIV/AIDS)
Year2021
Volume6
IssueSuppl 4
Pagese005554
Publication date2021-07-01
Open AccessYes
TypeARTICLE
VenueBMJ Global Health (JOURNAL)
Journal identifiersISSN: 2059-7908 • E-ISSN: 2059-7908
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/bmjgh-2021-005554
PMID34275875
OpenAlexW3185784365
LanguageEN
Citations received2
References cited37

BACKGROUND: Following success demonstrated with the HIV Self-Testing AfRica Initiative, HIV self-testing (HIVST) is being added to national HIV testing strategies in Southern Africa. An analysis of the costs of scaling up HIVST is needed to inform national plans, but there is a dearth of evidence on methods for forecasting costs at scale from pilot projects. Econometric cost functions (ECFs) apply statistical inference to predict costs; however, we often do not have the luxury of collecting large amounts of location-specific data. We fit an ECF to identify key drivers of costs, then use a simpler model to guide cost projections at scale. METHODS: We estimated the full economic costs of community-based HIVST distribution in 92 locales across Malawi, Zambia, Zimbabwe, South Africa and Lesotho between June 2016 and June 2019. We fitted a cost function with determinants related to scale, locales organisational and environmental characteristics, target populations, and per capita Growth Domestic Product (GDP). We used models differing in data intensity to predict costs at scale. We compared predicted estimates with scale-up costs in Lesotho observed over a 2-year period. RESULTS: The scale of distribution, type of community-based intervention, percentage of kits distributed to men, distance from implementer's warehouse and per capita GDP predicted average costs per HIVST kit distributed. Our model simplification approach showed that a parsimonious model could predict costs without losing accuracy. Overall, ECF showed a good predictive capacity, that is, forecast costs were close to observed costs. However, at larger scale, variations of programme efficiency over time (number of kits distributed per agent monthly) could potentially influence cost predictions. DISCUSSION: Our empirical cost function can inform community-based HIVST scale-up in Southern African countries. Our findings suggest that a parsimonious ECF can be used to forecast costs at scale in the context of financial planning and budgeting

Business · Econometric model · Econometrics · Economic growth · Economics · Economies of scale · Environmental health · Geography · Gross domestic product · Per capita · Population · Adolescent Sexual and Reproductive Health · HIV/AIDS Impact and Responses · HIV/AIDS Research and Interventions · Mathematics · Medicine · Marketing

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    Open Access•Monisha Sharma, Roger Ying et al.•Nature•2015

  • Examining the effects of HIV self‐testing compared to standard HIV testing services

    Open Access•Cheryl C Johnson, Caitlin Kennedy et al.•Journal of the International AIDS…•2017

  • Uptake, Accuracy, Safety, and Linkage into Care over Two Years of Promoting Annual Self-Testing for HIV in Blantyre, Malawi

    Open Access•Augustine Choko, Augustine T Choko et al.•PLoS Medicine•2015

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    Open Access•Lise Jamieson, Leigh F Johnson et al.•BMJ Global Health•2021

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    Open Access•Linda Sande, Linda Alinafe Sande et al.•BMJ Global Health•2021

  • Costs of accessing HIV testing services among rural Malawi communities

    Open Access•Linda Sande, Hendramoorthy Maheswaran et al.•AIDS Care•2018

  • HIV prevention programmes for female sex workers in Andhra Pradesh, India

    Open Access•Lalit Dandona, Pratap Sisodia et al.•BMC Public Health•2005

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    Open Access•Omar Galárraga, Richard G Wamai et al.•Health Policy and Planning•2017

Citations per year0.67
Citation span2023 - 2025 (3)
Highly citedNo

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