Cost-effectiveness of measles and rubella elimination in low-income and middle-income countries
Bibliographic Data
| ID | 21880004 |
|---|---|
| Authors | Ayala Levin (0000-0002-7417-7648, Morgan, Lewis & Bockius (United States), corresponding author), Ann Levin (Levin & Morgan LLC, Bethesda, Maryland, USA), Colleen Burgess (0000-0003-0393-0767, Phoenix (United States)), Stephanie Shendale (0000-0003-0126-2849, World Health Organization), Win Morgan (0000-0002-7834-3359, Morgan, Lewis & Bockius (United States)), Winthrop Morgan (Levin & Morgan LLC, Bethesda, Maryland, USA), Raymond Hutubessy (0000-0002-9286-5065, World Health Organization), Mark Jit (0000-0001-6658-8255, London School of Hygiene & Tropical Medicine) |
| Year | 2023 |
| Volume | 8 |
| Issue | 7 |
| Pages | e011526 |
| Publication date | 2023-07-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | BMJ Global Health (JOURNAL) |
| Journal identifiers | ISSN: 2059-7908 • E-ISSN: 2059-7908 |
| Publisher | BMJ (PUBLISHER • GB) |
| DOI | 10.1136/bmjgh-2022-011526 |
| PMID | 37429697 |
| OpenAlex | W4383872671 |
| Language | EN |
| Citations received | 1 |
| References cited | 24 |
BACKGROUND: Since 2000, the incidence of measles and rubella has declined as measles-rubella (MR) vaccine coverage increased due to intensified routine immunisation (RI) and supplementary immunisation activities (SIAs). The World Health Assembly commissioned a feasibility assessment of eliminating measles and rubella. The objective of this paper is to present the findings of cost-effectiveness analysis (CEA) of ramping up MR vaccination with a goal of eliminating transmission in every country. METHODS: We used projections of impact of routine and SIAs during 2018-2047 for four scenarios of ramping up MR vaccination. These were combined with economic parameters to estimate costs and disability-adjusted life years averted under each scenario. Data from the literature were used for estimating the cost of increasing routine coverage, timing of SIAs and introduction of rubella vaccine in countries. RESULTS: The CEA showed that all three scenarios with ramping up coverage above the current trend were more cost-effective in most countries than the 2018 trend for both measles and rubella. When the measles and rubella scenarios were compared with each other, the most cost-effective scenario was likely to be the most accelerated one. Even though this scenario is costlier, it averts more cases and deaths and substantially reduces the cost of treatment. CONCLUSIONS: The Intensified Investment scenario is likely the most cost-effective of the vaccination scenarios evaluated for reaching both measles and rubella disease elimination. Some data gaps on costs of increasing coverage were identified and future efforts should focus on filling these gaps
Congenital rubella syndrome · Environmental health · Measles · Measles vaccine · Rubella · Rubella vaccine · Vaccination · Immune responses and vaccinations · Medicine · Vaccine Coverage and Hesitancy · Virology and Viral Diseases · Immunology · Pediatrics
Estimating health opportunity costs in low-income and middle-income countries
Updating the evidence base on the operational costs of supplementary immunization activities for current and future accelerated disease control, elimination and eradication efforts
Comparing the health and social protection effects of measles vaccination strategies in Ethiopia
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2026 - 2026 (1) |
| Citation velocity | current |
| Highly cited | No |