Developing forecasting capacity for public health emergency management in Africa using syndemics approach
Lessons from the Covid-19 pandemic
Datos Bibliográficos
| ID | 21881378 |
|---|---|
| Autores | Kehinde Olawale Ogunyemi (0000-0001-5359-2263, Emory University, autor de correspondencia), Eniola Bamgboye (0000-0003-0500-8557, University of Ibadan), Adeola Fowotade (0000-0002-0224-7600, University of Ibadan), Fisayo Ogunwemimo (Babcock University), David Oladimeji Alao (Babcock University) |
| Año | 2022 |
| Volumen | 7 |
| Número | 8 |
| Páginas | e010148 |
| Fecha de publicación | 2022-08-01 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | BMJ Global Health (JOURNAL) |
| Identificadores de la revista | ISSN: 2059-7908 • E-ISSN: 2059-7908 |
| Editorial | BMJ (PUBLISHER • GB) |
| DOI | 10.1136/bmjgh-2022-010148 |
| PMID | 36028286 |
| OpenAlex | W4293124511 |
| Idioma | EN |
| Citas recibidas | 1 |
| Referencias citadas | 17 |
BACKGROUND Sex hormones have marked immunomodulatory properties and may play important roles in the etiology of various autoimmune diseases. OBJECTIVE To review the immunomodulatory effects of sex hormones, their roles in the etiology of autoimmune diseases, and their potential therapeutic applications. DISCUSSION Progesterone and androgens suppress the immune system, prolactin stimulates it, and estrogens can do either. Rheumatoid arthritis tends to improve during pregnancy, during estrogen replacement therapy, and during treatment with estrogen-containing oral contraceptives. Systemic lupus erythematosus is aggravated by pregnancy and probably by estrogens. Therapy of rheumatoid arthritis with estrogens has not been promising, but testosterone replacement in men has shown modest benefits. In lupus, 19-nortestosterone has had little or no benefit, but danazol has been helpful in some patients, and encouraging preliminary results were obtained with dehydroepiandrosterone. CONCLUSIONS We strongly recommend estrogen replacement therapy to prevent postmenopausal osteoporosis in women with rheumatoid arthritis. Younger women with rheumatoid arthritis can undergo pregnancy or use estrogen-containing contraceptives. Estrogens can be used in lupus only with great caution. Recommendations regarding other hormones and other diseases are less firm, but research is continuing in this area
Antibody · Biology · Disease · Estrogen · Etiology · Lupus erythematosus · Osteoporosis · Pregnancy · Rheumatoid arthritis · Systemic lupus erythematosus · Liver Disease Diagnosis and Treatment · Medicine · SARS-CoV-2 and COVID-19 Research · Systemic Lupus Erythematosus Research · Immunology · Internal Medicine
Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China
The Fair Guiding Principles for scientific data management and stewardship
Covid-19 pandemic in Africa’s island nations during the first 9 months
Covid-19 mortality in women and men in sub-Saharan Africa
An in-depth statistical analysis of the Covid-19 pandemic’s initial spread in the WHO African region
The potential effects of widespread community transmission of Sars-CoV-2 infection in the World Health Organization African Region
Leveraging human resources for outbreak analysis
The Syndemics of Emergency
| Obras citantes distintas | 1 |
|---|---|
| Citas por año | 1 |
| Intervalo de citas | 2025 - 2025 (1) |
| Velocidad de citación | recent |
| Altamente citado | No |
| Tipos de cita | Neutras: 1 |