Regional burden of chronic kidney disease in North Africa and Middle East during 1990–2019; Results from Global Burden of Disease study 2019

Bibliographic Data

ID22067081
AuthorsOzra Tabatabaei-Malazy (0000-0003-0188-9721, Tehran University of Medical Sciences), Sahar Saeedi Moghaddam (0000-0002-3112-9179, Tehran University of Medical Sciences), Patricia Khashayar (0000-0001-7525-8418, Imec the Netherlands), Mohammad Keykhaei (0000-0001-5728-7848, Northwestern University), Yeganeh Sharifnejad Tehrani (Tehran University of Medical Sciences), Mohammad‐Reza Malekpour (0000-0002-8648-5402, Tehran University of Medical Sciences), Mohammad-Reza Malekpour, Zahra Esfahani (0000-0002-0023-1568, University of Social Welfare and Rehabilitation Sciences), Mohammad‐Mahdi Rashidi (0000-0002-7460-6000, Tehran University of Medical Sciences), Mohammad-Mahdi Rashidi, Ali Golestani (0000-0002-5192-0435, Tehran University of Medical Sciences), Parnian Shobeiri (0000-0002-5282-3282, Tehran University of Medical Sciences), Mana Moghimi (Tehran University of Medical Sciences), Fateme Gorgani (0000-0002-6938-3447, Tehran University of Medical Sciences), Elham Abdolhamidi (0000-0001-7679-6285, Tehran University of Medical Sciences), Farshad Farzadfar (0000-0001-8288-4046, Tehran University of Medical Sciences), Bagher Larijani (0000-0001-5386-7597, Tehran University of Medical Sciences, corresponding author)
Year2022
Volume10
Pages1015902-1015902
Publication date2022-10-11
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.1015902
PMID36304241
OpenAlexW4304166127
LanguageEN
References cited29

Objectives: Updating burden data of chronic kidney disease (CKD) as one of the most prevalent non-communicable diseases is essential for proper provision of healthcare by policymakers. We aimed to estimate the burden of CKD and its attributed burden in North Africa and Middle East region (NAME) during 1990-2019. Methods: The CKD-related Global Burden of Disease (GBD) 2019 estimates were extracted from Health Metrics and Evaluation (IHME) website. Results: In 2019, 2,034,879 new CKD cases (95% Uncertainty interval 1,875,830 to 2,202,724) with an age-standardized incidence rate of 447.5 (415.1 to 482.8) per 100,000 was reported, showing a 70.9% increase in the past 30 years. CKD led to 111,812 deaths (96,421 to 130,853) with an age-standardized rate of 30.4 (26.3 to 35.4) per 100,000. The highest increase and decrease in the mortality rate were estimated in Morocco 21.8% (-8.9 to 51.6) and Kuwait -41.5% (-51.2 to -29.1). In 2019, CKD was responsible for 744.4 (646.1 to 851.8) age-standardized disability-adjusted life years (DALYs), mostly contributed to "other and unspecified causes" [237.2 (191.1 to 288.4)], type 2 diabetes [205.9 (162.4 to 253.6)], and hypertension [203.3 (165.8 to 243)]. An increase was noted in DALYs from ages 25-29 and surged with an accelerating pattern by age. Kidney dysfunction, high systolic blood pressure, and high body mass index ranked as the top three risk factors for the disorder. Conclusions: Our study raised an alarm regarding the increasing CKD burden in NAME. There is an urgency to deal with hypertension and overweight/obesity at the primary care level, implementing CKD screening for at-risk groups, and facilitating the accessibility to appropriate treatments

Blood pressure · Body mass index · Burden of disease · Confidence interval · Diabetes mellitus · Disease · Disease burden · Environmental health · Kidney disease · Type 2 diabetes · Blood Pressure and Hypertension Studies · Chronic Kidney Disease and Diabetes · Demography · Dialysis and Renal Disease Management · Medicine · Endocrinology · Gerontology · Internal Medicine

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