Evaluation of Rapid Antigen Tests Using Nasal Samples to Diagnose Sars-CoV-2 in Symptomatic Patients
Bibliographic Data
| ID | 22067712 |
|---|---|
| Authors | Manaf AlQahtani (0000-0002-1523-0429, Royal College of Surgeons in Ireland - Bahrain, corresponding author), Abdulkarim Abdulrahman (0000-0002-7331-388X, Bahrain Center for Strategic International and Energy Studies), Fathi Mustafa (Royal College of Surgeons in Ireland - Bahrain), Abdulla Alawadhi (0000-0001-7014-3056, Bahrain Center for Strategic International and Energy Studies), Abdulla I Alawadhi, Batool Alalawi (Ministry of Health), Saad I Mallah (0000-0002-2234-1530, Royal College of Surgeons in Ireland - Bahrain) |
| Year | 2022 |
| Volume | 9 |
| Pages | 728969-728969 |
| Publication date | 2022-01-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2021.728969 |
| PMID | 35096725 |
| OpenAlex | W4206131758 |
| Language | EN |
| Citations received | 1 |
| References cited | 25 |
INTRODUCTION: The best way to mitigate an outbreak besides mass vaccination is via early detection and isolation of infected cases. As such, a rapid, cost-effective test for the early detection of COVID-19 is required. METHODS: The study included 4,183 mildly symptomatic patients. A nasal and nasopharyngeal sample obtained from each patient was analyzed to determine the diagnostic ability of the rapid antigen detection test (RADT, nasal swab) in comparison with the current gold-standard (RT-PCR, nasopharyngeal swab). RESULTS: < 0.001). Stratified analysis showed that the sensitivity of the RADT improved significantly when lowering the cut-off RT-PCR Ct value to 24. CONCLUSION: Our study's results support the potential use of nasal swab RADT as a screening tool in mildly symptomatic patients, especially in patients with higher viral loads
Antigen · Vaccination · Virus · Virus isolation · Biosensors and Analytical Detection · Medicine · SARS-CoV-2 and COVID-19 Research · SARS-CoV-2 detection and testing · Immunology · Internal Medicine · Virology
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |