Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019

Bibliographic Data

ID22068445
AuthorsWangcheng Xie (Tongji University), Tingsong Yang (0000-0002-3374-1142, Tongji University), Jieliang Zuo (Tongji University), Zhilong Ma (0000-0002-6946-8686, Shanghai Jiao Tong University), Weidi Yu (0000-0001-5200-8459, Tongji University), Zhengyu Hu (0000-0003-1721-7321, Tongji University), Zhenshun Song (0000-0002-7124-1579, Tongji University, corresponding author)
Year2022
Volume10
Pages941284-941284
Publication date2022-07-13
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.941284
PMID35910886
OpenAlexW4285393618
LanguageEN
Citations received2
References cited48

Background: Gastrointestinal (GI) cancers are an important component of the tumor. This study aimed to investigate the burden of six major GI cancers in China and globally from 1990 to 2019. Methods: We conducted a cross-sectional study based on the Global Burden of Disease Study (GBD) 2019. Indicators on incidence, deaths, disability-adjusted life-years (DALYs), and risk factors for esophageal, stomach, liver, pancreatic, colon and rectum, and gallbladder and biliary tract cancers were collected and analyzed for time trends. The contribution of each cancer and the proportion of cases in China among global cases were further reported. Results: Global incidence cases, death cases, and DALYs of GI cancers showed an overall ascending trend over the past 30 years, but there was temporal and geographical variation across cancer types. By 2019, colon and rectum cancer had overtaken stomach cancer as the most burdensome GI cancer globally. However, stomach cancer narrowly continued to be the most burdensome GI in China. In addition, the proportion of incidence and death cases of stomach, pancreatic, colon and rectum, and gallbladder and biliary tract cancers among global cases had further increased. It was noteworthy that the burden of liver cancer in China has been alleviated significantly. Conclusion: GI cancers remain a major public health problem in China and globally. Despite the temporal and geographic diversity of different cancers, targeted primary and secondary prevention are still necessary for the future to face these unknown challenges

Cancer · Colorectal cancer · Gallbladder · Pancreatic cancer · Rectum · Stomach · Stomach cancer · Esophageal Cancer Research and Treatment · Gastric Cancer Management and Outcomes · Medicine · Multiple and Secondary Primary Cancers · Gastroenterology · Internal Medicine

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