Association between oxidative balance score and prostate specific antigen among older US adults
Bibliographic Data
| ID | 22068610 |
|---|---|
| Authors | Jintao Li (0000-0003-1552-8118, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture), Chao Yang (0000-0003-3623-4311, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture), Kui Xiang (0000-0003-3600-8779, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, corresponding author) |
| Year | 2024 |
| Volume | 11 |
| Pages | 1336657-1336657 |
| Publication date | 2024-01-22 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2023.1336657 |
| PMID | 38317687 |
| OpenAlex | W4391108816 |
| Language | EN |
| References cited | 29 |
Objective Oxidative Balance Score (OBS) is an index affecting the oxidative stress of dietary and lifestyle factors. We aimed to explore the association of OBS with prostate specific antigen (PSA) among older males. Methods A total of 5,136 samples were collected in this study to investigate the relationship between OBS and PSA from the National Health and Nutrition Examination Survey. Logistic regression models and restricted cubic spline were used to assess the associations between OBS and PSA. Results Compared with the Q1 group, the odds ratios for the association between OBS and PSA were 1.005 (1.003, 1.009), 1.003 (1.001, 1.006), and 1.001 (0.978, 1.022) for Q2, Q3, and Q4, respectively. In the age-specific analyses, the association was significant among individuals aged 65 years old and over: the odds ratios for the association between OBS and PSA were 1.019 (1.005, 1.028), 1.028 (1.018, 1.039), and 1.038 (1.022, 1.049) for Q2, Q3, and Q4, respectively. But it was not significant among individuals aged less than 65 years old: the odds ratios for the association between OBS and PSA were 1.016 (0.995, 1.026), 1.015 (0.985, 1.022), and 0.988 (0.978, 1.016) for Q2, Q3, and Q4, respectively. The restricted cubic splines also indicated a nonlinear relationship between OBS and PSA among individuals aged 65 years old and over ( P overall = 0.006, P nonlinear = 0.021). Conclusion Our findings provide evidence that OBS is positively associated with higher levels of PSA among older adults. Further large-scale prospective cohort studies are needed to verify our findings
Cancer · Environmental health · Logistic regression · National Health and Nutrition Examination Survey · Odds · Odds ratio · Population · Prostate cancer · Prostate-specific antigen · Antioxidant Activity and Oxidative Stress · Demography · Exercise and Physiological Responses · Medicine · Paraoxonase enzyme and polymorphisms · Internal Medicine
| Highly cited | No |
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