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A bibliometric analysis of the 100 most cited articles describing Sars-CoV-2 variants

Bibliographic Data

ID22069172
AuthorsYahui Zhang (0000-0003-1895-9191, Aerospace Center Hospital), Meijing Feng (Aerospace Center Hospital), Yongmei He (0000-0001-8072-7514, Aerospace Center Hospital), Fangming Liu (0000-0002-9601-4612, Aerospace Center Hospital), Rui Ma (0000-0002-3367-674X, Aerospace Center Hospital, corresponding author)
Year2022
Volume10
Pages966847-966847
Publication date2022-08-26
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.966847
PMID36091553
OpenAlexW4293217605
LanguageEN
References cited27

Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with mutations in the spike protein has risen concerns about the efficacy of infection- or vaccine-induced antibodies and has posed a serious threat to global public health, education, travel and economy. Few studies have described the detailed characterizations of highly cited articles on SARS-CoV-2 variants. Objective: To identify and characterize the 100 most-cited articles in SARS-CoV-2 variants research. Design and methods: the following parameters: publication number over year, number of citations, type of articles, authors, journal, journal impact factor, country, and topics covered in articles. In addition, clinical trials in these articles were also analyzed. Results: The majority of articles (66%) were published in 2021. Number of citations of the 100 most cited articles ranged from 1720 to 75 (median: 178.5). Mutations in the S protein such as D614G mutation and the B.1.1.7 (UK) and B.1.351 (South Africa) were the dominant variants in the 100 most cited articles. The United States, the United Kingdom, and South Africa had the strongest collaboration in the contribution of publication. Science, Cell, Nature and New England Journal of Medicine were mostly cited and the main direction in these top journals were vaccine neutralizing tests and efficacy evaluation studies. Response of antibody neutralization tests against variants was always weakened due to the presence of variants but the results of clinical trials were encouraging. Genomics information, spike protein structure confirmation and neutralization studies evaluating antibody resistance were highly represented in the 100 most cited articles in SARS-CoV-2 variants literature. Conclusions and relevance: Altogether, genomic information, epidemiology, immune neutralization, and vaccine efficacy studies of COVID-19 variants are the main research orientations in these articles and relevant results have been published in influential journals. Given the continuous evolution of the SARS-CoV-2 and the constant development in our understanding of the impact of variants, current working strategies and measures may be periodically adjusted

Bibliometrics · Family medicine · Impact factor · Library science · MEDLINE · Pathology · Political science · Web of science · Computer Science · COVID-19 Clinical Research Studies · Law · Medicine · SARS-CoV-2 and COVID-19 Research · vaccines and immunoinformatics approaches

  • Sars-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

    Open Access•Markus Hoffmann, Hannah Kleine-Weber et al.•Cell•2020

  • Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

    Open Access•Fernando P Polack, Stephen J Thomas et al.•New England Journal of Medicine•2020

  • Citation Analysis as a Tool in Journal Evaluation

    Open Access•Eugene Garfield•Science•1972

  • Bibliometric Indicators

    Valérie Durieux, Pierre Alain Gevenois•Radiology•2010

Highly citedNo

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Open DOIOpen Access
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