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Three-year nationwide survey of microbiology laboratory equipment conditions in China’s CDC

Setting new benchmarks

Bibliographic Data

ID22069256
AuthorsPeihua Niu (0000-0001-5930-4234, National Institute for Viral Disease Control and Prevention), Zhenlu Sun (0000-0002-6153-0860), Yu Zhang (0000-0002-0059-270X, National Institute for Viral Disease Control and Prevention), Dapeng Zhang (0000-0002-0798-7982, National Institute for Viral Disease Control and Prevention), Ruiqing Zhang (0000-0002-5087-2734, National Institute for Viral Disease Control and Prevention), Yiming Zhao (0000-0001-8182-456X, National Institute for Viral Disease Control and Prevention), Fengyu Tian (0000-0003-1880-6603, National Institute for Viral Disease Control and Prevention), Jieqiong Zhang (0000-0002-6774-5360, National Institute for Viral Disease Control and Prevention), Hongmei Zheng (0009-0009-4796-3764, National Institute for Viral Disease Control and Prevention), Jianqiang Guo (0000-0002-5338-4744, National Institute for Viral Disease Control and Prevention), Ping Cheng (0000-0002-1964-2471, National Institute for Viral Disease Control and Prevention), Xuejun Ma (0000-0002-1292-3449, National Institute for Viral Disease Control and Prevention, corresponding author), Ji Wang (0000-0002-3447-9107), Ji Guang Wang (National Institute for Viral Disease Control and Prevention, corresponding author)
Year2026
Volume13
Pages1679072-1679072
Publication date2026-01-13
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1679072
PMID41607897
OpenAlexW7123350475
LanguageEN
References cited30

Background: This study evaluates the penetration and evolution of laboratory equipment in China's Centers for Disease Control and Prevention (CDCs) from 2021 to 2023, establishing benchmarks for optimal equipment configuration and operational capacity enhancement. Methods: Data were collected from CDCs at provincial, municipal, and county levels over three years using stratified sampling and structured questionnaires. These captured information on equipment penetration and user satisfaction. Statistical analyses, including Chi-square tests, ANOVA, and Fisher's exact tests, identified trends and disparities in equipment distribution across administrative tiers. Results: Analysis of 540 questionnaires from 376 CDCs showed that essential equipment like Biological Safety Cabinets (BSCs) and qPCR machines achieved over 95% penetration across all levels. Municipal CDCs reported the largest increases in equipment acquisition, followed by provincial CDCs, with minimal changes at the county level. The penetration of domestic qPCR machines rose from 21.8% in 2021% to 28.3% in 2023, with domestic brands closing the gap with international counterparts. Post-COVID-19, strategies for optimizing equipment utilization appear promising. Conclusion: This study provides a valuable dataset on microbiology laboratory equipment in China's CDCs, revealing distinct patterns in equipment retention and acquisition. Disparities in qPCR machine and High-throughput Sequencer (HTS) penetration and satisfaction rates highlight a shift toward domestic manufacturing. The findings offer essential benchmarks for optimizing laboratory infrastructure and enhancing public health responses

Clinical microbiology · Health care · MEDLINE · Public health · Bacterial Identification and Susceptibility Testing · Clinical Laboratory Practices and Quality Control · Infection Control and Ventilation

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