Cluster analysis for symptomatic management of Neisseria gonorrhoea and Chlamydia trachomatis in sexually transmitted infections related clinics in China

Bibliographic Data

ID22069441
AuthorsNing Ning (0000-0002-8297-1518, Shantou University), Rongxing Weng (0000-0003-1792-2186, Shenzhen Nanshan Center for Chronic Disease Control), Chunlai Zhang (0000-0002-7242-9071, Shenzhen Nanshan Center for Chronic Disease Control), Lizhang Wen (Shenzhen Nanshan Center for Chronic Disease Control), Honglin Wang (0000-0001-6941-4998, Shenzhen Nanshan Center for Chronic Disease Control), Jianbin Ye (0000-0001-5471-2458, Shenzhen Nanshan Center for Chronic Disease Control), Jing Li (0000-0001-7792-4322, Shenzhen Nanshan Center for Chronic Disease Control), Xiang‐sheng Chen (0000-0003-3927-2065, Chinese Academy of Medical Sciences & Peking Union Medical College), Xiangsheng Chen (0000-0002-0880-579X), Yumao Cai (0000-0002-8098-8244, Shenzhen Nanshan Center for Chronic Disease Control, corresponding author)
Year2022
Volume10
Pages1005481-1005481
Publication date2022-11-17
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.1005481
PMID36466460
OpenAlexW4309606892
LanguageEN
Citations received1
References cited32

Objective: (CT) and to identify which cluster of symptoms was associated with a higher risk of NG and CT. Study design: From 15 April to 16 May 2018, a cross-sectional study was conducted, and patients attending sexually transmitted infections (STI) related clinics were recruited from 22 medical institutions in six districts of Shenzhen city. Methods: A structured questionnaire was used to collect social-demographic information as well as STI symptoms, and urine samples were collected for nucleic acid detection. Cluster analysis and logistic regression were applied. Results: Among 8,207 participants, the prevalence of CT and NG infection was 9.04% (742/8,207) and 2.36% (194/8,207), respectively. Among male outpatients, four clusters with distinct symptomatic patterns were identified. Unmarried, having casual sexual partners in the past 6 months, cluster 2 (OR = 6.70, 95% CI = 3.36-13.35) and cluster 4 (OR = 24.53, 95% CI = 12.96-46.44) were risk factors associated with NG infection. Unmarried, cluster 2 (OR = 2.54, 95% CI = 1.83-3.53) and cluster 4 (OR = 3.31, 95% CI = 2.37-4.61) were risk factors associated with CT infection. Among female outpatients, five clusters with distinct symptomatic patterns were identified. Aged 24 years or below and cluster 3 (OR = 3.68, 95% CI = 1.61-8.39) were risk factors associated with NG infection. Aged 24 years or below, unmarried, having a high school/secondary technical school education, and having junior high school or below education were risk factors associated with CT infection. Conclusion: The cluster of symptoms integrated into risk assessment for CT and NG infections suggests a new strategy of symptomatic management. Healthcare providers in STI clinics and resource-limited places may use this strategy to identify more potential patients and deliver adequate, acceptable, and equitable STI care for outpatients with a high risk of STI

Biology · Chlamydia · Chlamydia trachomatis · Cross-sectional study · Gonorrhea · Gynecology · Logistic regression · Neisseria gonorrhoeae · Pathology · Adolescent Sexual and Reproductive Health · Demography · Medicine · Reproductive tract infections research · Syphilis Diagnosis and Treatment · Immunology · Internal Medicine

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