Risk of newly diagnosed interstitial lung disease after Covid-19 and impact of vaccination
A nationwide population-based cohort study
Bibliographic Data
| ID | 22069474 |
|---|---|
| Authors | Bo-Guen Kim, Bo‐Guen Kim (0000-0003-0800-4324, Hanyang University), Hyun Lee (0000-0001-7909-6866, Hanyang University), Cho Yun Jeong (0009-0003-8281-4285, Jeonbuk National University), Sang Woo Yeom (0000-0002-3340-6184, Jeonbuk National University), Dong Won Park (0000-0002-4538-6045, Hanyang University), Tai Sun Park (0000-0001-7383-7934, Hanyang University), Ji‐Yong Moon (0000-0003-2459-3448, Hanyang University), Ji-Yong Moon, Tae‐hyung Kim (0000-0002-3863-7854, Hanyang University), Tae-Hyung Kim (0000-0002-5045-4401), Jang Won Sohn (0000-0001-7132-2988, Hanyang University), Ho Joo Yoon (0000-0002-4645-4863, Hanyang University), Jong Seung Kim (0000-0003-3477-1172, Jeonbuk National University Hospital, corresponding author), Sang‐Heon Kim (0000-0001-8398-4444, Hanyang University, corresponding author), Sang-Heon Kim |
| Year | 2024 |
| Volume | 11 |
| Pages | 1295457-1295457 |
| Publication date | 2024-01-08 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2023.1295457 |
| PMID | 38259763 |
| OpenAlex | W4390670135 |
| Language | EN |
| Citations received | 1 |
| References cited | 43 |
Objectives: Previous studies suggested that coronavirus disease 2019 (COVID-19) could lead to pulmonary fibrosis, but the incidence of newly diagnosed interstitial lung disease (ILD) after COVID-19 is unclear. We aimed to determine whether COVID-19 increases the risk of newly diagnosed ILD and whether vaccination against COVID-19 can reduce this risk. Methods: This retrospective cohort study used data from the Korean National Health Insurance claim-based database. Two study groups and propensity score (PS)-matched control groups were constructed: Study 1: participants diagnosed with COVID-19 (COVID-19 cohort) and their PS-matched controls; Study 2: COVID-19 vaccinated participants (vaccination cohort) and their PS-matched controls. Results: In Study 1, during a median 6 months of follow-up, 0.50% of the COVID-19 cohort (300/60,518) and 0.04% of controls (27/60,518) developed newly diagnosed ILD, with an incidence of 9.76 and 0.88 per 1,000 person-years, respectively. The COVID-19 cohort had a higher risk of ILD [adjusted hazard ratio (aHR), 11.01; 95% confidence interval (CI), 7.42-16.32] than controls. In Study 2, the vaccination cohort had a lower risk of newly diagnosed ILD than controls (aHR, 0.44; 95% CI, 0.34-0.57). Conclusion: Using nationwide data, we demonstrated that COVID-19 was associated with a higher incidence rate of newly diagnosed ILD, but that this risk could be mitigated by COVID-19 vaccination
2019-20 coronavirus outbreak · Cohort · Cohort study · Disease · Environmental health · Intensive care medicine · Outbreak · Population · Vaccination · Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis · Long-Term Effects of COVID-19 · Medicine · SARS-CoV-2 and COVID-19 Research · Internal Medicine · Pediatrics · Virology
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,5 |
| Citation span | 2024 - 2024 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |