Multiple introduced lineages and the single native lineage co-driving the four waves of the Covid-19 pandemic in West Africa

Datos Bibliográficos

ID22069686
AutoresLiping Gao (0000-0001-8542-6171, National Institute for Viral Disease Control and Prevention), Canjun Zheng (0000-0001-6822-8755, Chinese Center For Disease Control and Prevention), Qi Shi (0000-0001-5793-3440, National Institute for Viral Disease Control and Prevention), Lili Wang (0000-0002-0082-8487, Chinese Center For Disease Control and Prevention), Alie Tia, Jone Ngobeh, Jone Jama Kpanda Ngobeh (0000-0002-5082-6930), Zhiguo Liu (0000-0002-8485-7356, National Institute for Communicable Disease Control and Prevention, autor de correspondencia), Xiaoping Dong (0000-0002-2302-7711, National Institute for Viral Disease Control and Prevention, autor de correspondencia), Zhenjun Li (0000-0003-4846-5440, Chinese Center For Disease Control and Prevention, autor de correspondencia)
Año2022
Volumen10
Páginas957277-957277
Fecha de publicación2022-09-15
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaFrontiers in Public Health (JOURNAL)
Identificadores de la revistaISSN: 2296-2565 • E-ISSN: 2296-2565
EditorialFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.957277
PMID36187679
OpenAlexW4296100747
IdiomaEN
Citas recibidas1
Referencias citadas45

Coronavirus disease 2019 (COVID-19) has become a vast burden on public health and socioeconomics in West Africa, but the epidemic situation is unclear. Therefore, we conducted a retrospective analysis of the positive rate, death rate, and diversity of SARS-CoV-2. As of March 31, 2022, a total of 894,813 cases of COVID-19 have been recorded, with 12,028 deaths, both of which were distributed in all 16 countries. There were four waves of COVID-19 during this period. Most cases were recorded in the second wave, accounting for 34.50% of total cases. These data suggest that although West Africa seems to have experienced a low and relatively slow spread of COVID-19, the epidemic was ongoing, evolving with each COVID-19 global pandemic wave. Most cases and most deaths were both recorded in Nigeria. In contrast, the fewest cases and fewest deaths were reported, respectively, in Liberia and Sierra Leone. However, high death rates were found in countries with low incidence rates. These data suggest that the pandemic in West Africa has so far been heterogeneous, which is closely related to the infrastructure of public health and socioeconomic development (e.g., extreme poverty, GDP per capita, and human development index). At least eight SARS-CoV-2 variants were found, namely, Delta, Omicron, Eta, Alpha, Beta, Kappa, Iota, and Gamma, which showed high diversity, implicating that multiple-lineages from different origins were introduced. Moreover, the Eta variant was initially identified in Nigeria and distributed widely. These data reveal that the COVID-19 pandemic in the continent was co-driven by both multiple introduced lineages and a single native lineage. We suggest enhancing the quarantine measures upon entry at the borders and implementing a genome surveillance strategy to better understand the transmission dynamics of the COVID-19 pandemic in West Africa

Disease · Geography · Mortality rate · Pandemic · Pathology · Per capita · Population · Public health · Sierra leone · Socioeconomic status · Socioeconomics · Sociology · COVID-19 diagnosis using AI · COVID-19 epidemiological studies · Demography · Medicine · SARS-CoV-2 and COVID-19 Research