Factors associated with medication interruption among outpatients with severe mental illness exposed to Covid-19
Bibliographic Data
| ID | 22070822 |
|---|---|
| Authors | J Jiao (0000-0002-1058-8026, Sichuan University), Yuanyi Ji (Sichuan University), Hua Ren (The Fourth People's Hospital), Yanni Hao (0000-0002-2300-9951, Sichuan University), Xiaoling Shen (0000-0003-1688-7913, Sichuan University), Zaiquan Dong (0000-0003-0226-239X, Sichuan University, corresponding author) |
| Year | 2023 |
| Volume | 11 |
| Pages | 1086863-1086863 |
| Publication date | 2023-03-28 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2023.1086863 |
| PMID | 37056653 |
| OpenAlex | W4361208322 |
| Language | EN |
| References cited | 29 |
Many patients with severe mental illness (SMI) relapsed and deteriorated during the COVID-19 pandemic, as they experienced medication interruption. This study aimed to investigate factors affecting medication interruption in patients with SMI during the COVID-19 pandemic. A total of 2,077 patients with SMI participated in an online survey on medication interruption during the COVID-19 outbreak. The questionnaire comprised six parts: basic demographic information, COVID-19 exposure, state of disease, medication compliance before COVID-19, medication interruption during COVID-19, and the specific impact and needs. A total of 2,017 valid questionnaires were collected. Nearly 50% of patients with SMI have been affected to varying degrees of life expectancy and treatment. Among them, 74 patients stopped taking medicines for more than 14 days without a prescription. Logistic regression analysis showed that cohabitant exposure [OR = 26.629; 95% CI (3.293–215.323), p = 0.002], medication partial compliance and non-compliance pre-COVID-19 [OR = 11.109; 95% CI (6.093–20.251), p < 0.001; OR = 20.115; 95% CI (10.490–38.571), p < 0.001], and disease status [OR = 0.326; 95% CI (0.188–0.564), p < 0.001] were related to medication interruption. More than 50% of the patients wanted help in taking medications, follow-up, and receiving more financial support and protective materials. We found that the daily lives of patients with SMI were much more susceptible to impact during the pandemic. Patients with a history of partial or non-medication compliance before COVID-19 and an unstable disease state are more easily affected by pandemics and epidemics and need extra attention should similar large-scale outbreaks occur in the future
Disease · Logistic regression · Medical prescription · Mental health · Mental illness · Outbreak · Pandemic · Psychiatry · COVID-19 and Mental Health · COVID-19 Clinical Research Studies · Long-Term Effects of COVID-19 · Medicine · Emergency Medicine · Internal Medicine
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| Citation velocity | historical |
|---|---|
| Highly cited | No |