Comparative efficacy of traditional non-pharmacological add-on treatments in patients with stable chronic obstructive pulmonary disease
A systematic review and network meta-analysis
Bibliographic Data
| ID | 22073143 |
|---|---|
| Authors | Ji-Ae Roh (0000-0001-5125-0999), Jungtae Leem (0000-0003-3300-5556), Beom-Joon Lee (0000-0003-4205-1175), Kwan-Il Kim (0000-0002-8071-3881), Hee-Jae Jung (0000-0001-7384-6881) |
| Year | 2025 |
| Volume | 13 |
| Publication date | 2025-02-21 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2025.1410342 |
| Language | EN |
| References cited | 100 |
Chronic obstructive pulmonary disease (COPD) is a major global public health concern. In this study, we examined the comparative efficacy of non-pharmacological interventions within East Asian traditional medicine (EATM-NPI) for enhancing pulmonary function and exercise capacity in patients with stable COPD. A thorough search of electronic databases conducted until May 22, 2022, identified studies employing EATM-NPI in such patients. The evaluation focused on the impact adjunctive therapies on pulmonary function (forced expiratory volume in 1 s [FEV 1 ]) and exercise capacity (6-min walking distance [6MWD]). The qualitative assessment encompassed 142 studies, with 133 studies included in one of three network meta-analyses. Participants, aged 49–76 years, ranged from 9 to 139 per group, predominantly from China (87.7% of studies). Overall study quality was generally low, and reported adverse events were mild. Notably, moxibustion and qigong adjunctive therapies demonstrated significant improvements in FEV 1 (L) and FEV 1 (%). Additionally, chuna, acupuncture, qigong and moxibustion adjunctive therapies were associated with significant improvements in 6MWD. In conclusion, EATM-NPI adjunctive therapy, when combined with standard pharmacological treatment, exhibited effects on pulmonary function and exercise capacity in patients with COPD. Systematic review registration: The protocol was registered with PROSPERO (CRD42023389431), https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023389431
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010
An Official American Thoracic Society/European Respiratory Society Statement
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010
The PRISMA Extension Statement for Reporting of Systematic Reviews Incorporating Network Meta-analyses of Health Care Interventions
Moxibustion Has a Positive Effect on Pulmonary Fibrosis
Global and regional estimates of COPD prevalence
Traditional Korean Medicine Home Care for the Older Adults during the Covid-19 Pandemic in South Korea
| Citation velocity | historical |
|---|---|
| Highly cited | No |