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Vaccine hesitancy and related factors among South African adults in 2021

Unpacking uncertainty versus unwillingness

Bibliographic Data

ID22074691
AuthorsRonel Sewpaul (0000-0002-2523-1222, Human Sciences Research Council, corresponding author), Sibusiso Sifunda (0000-0002-8766-7240, Human Sciences Research Council), Razia Gaida (0000-0003-2895-4669), Tholang Mokhele (0000-0002-9087-7951, Human Sciences Research Council), Inbarani Naidoo (0000-0001-7590-0618, Human Sciences Research Council), Sasiragha Priscilla Reddy (University of KwaZulu-Natal)
Year2023
Volume11
Pages1233031-1233031
Publication date2023-11-03
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1233031
PMID38026341
OpenAlexW4388297094
LanguageEN
Citations received3
References cited28

Background: Amidst widespread public health recommendations and availability of COVID-19 vaccinations, half of South African adults are vaccinated against COVID-19. This study investigated the socio-behavioral determinants of vaccine hesitancy in South Africa, where vaccine hesitancy was separated into unwilling ness and uncertainty to take a COVID-19 vaccine. Methods: Data was collected from a large-scale public survey during June-October 2021 that included online and telephonic surveys. Vaccination hesitancy was based on the question "When available, would you take the COVID 19 vaccine?," with responses categorized into those who were willing, unwilling, and uncertain about taking a COVID-19 vaccine. Multinomial regression examined the association between socio-behavioral variables and vaccine hesitancy. Results: = 16,988). Younger age, White and Colored population groups, no influenza vaccination history, previous vaccination refusal, knowing someone who experienced a serious vaccination side-effect, misperceptions about vaccine benefits, cultural or religious discouragement from taking a COVID-19 vaccination, lack of governmental confidence, concerns about side-effects, perceived lack of safety information, and lack of trust in the pharmaceutical industry and in the information from health care providers were all associated with higher odds of being uncertain and unwilling to take a COVID-19 vaccination. Strengths of association for unwillingness and uncertainty varied by the explanatory variables. Concern about effectiveness due to fast development was associated with uncertainty to take the vaccine but not with unwillingness. Concerns about side-effects had stronger associations with uncertainty than with unwillingness, while previous vaccine refusal, misperceptions of the protective benefits of vaccines, White population group, religious/cultural discouragement, and lack of trust in the pharmaceutical industry and health care providers' information had stronger associations with unwillingness than uncertainty. Conclusion: The determinants of COVID-19 vaccine hesitancy should be addressed in interventions to improve vaccine uptake. Public health interventions and health communication can be prioritized and tailored to the different forms of vaccination hesitancy

Environmental health · Family medicine · Influenza vaccine · Misinformation · Odds ratio · Political science · Population · Public health · Vaccination · COVID-19 and Mental Health · Demography · Medicine · Misinformation and Its Impacts · Nursing · Vaccine Coverage and Hesitancy · Immunology

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Citations per year1.5
Citation span2024 - 2026 (3)
Highly citedNo

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