Is first pregnancy age associated with hypertension in the Chinese rural women population

Bibliographic Data

ID22075286
AuthorsZhen Du (0000-0001-8359-6118, Third Affiliated Hospital of Zhengzhou University), Xueyan Wu (0000-0002-2275-3834, Zhengzhou University), Wei Liao (0000-0001-9987-3546, Zhengzhou University), Ze Hu (0009-0001-9608-5429, Zhengzhou University), Jing Yang (0009-0004-1715-4513, Zhengzhou University), Xiaokang Dong (0000-0001-5259-788X, Zhengzhou University), Hongfei Zhao (0000-0001-9507-3162, Zhengzhou University), Xiaotian Liu (0009-0009-6737-5353, Zhengzhou University), Chongjian Wang (0000-0001-5091-6621, Zhengzhou University, corresponding author), Bing Zhao (0000-0001-5714-3756, Third Affiliated Hospital of Zhengzhou University, corresponding author)
Year2023
Volume11
Pages1120732-1120732
Publication date2023-04-17
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1120732
PMID37139358
OpenAlexW4366086694
LanguageEN
References cited28

Introduction: The purpose of this study was to investigate the relationship between first pregnancy age and hypertension later in the life of women from Chinese rural areas. Methods: In total, 13,493 women were enrolled in the Henan Rural Cohort study. Logistic regression and linear regression were used to evaluate the association between first pregnancy age and hypertension and blood pressure indicators [including systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP)]. The restricted cubic spline was used to examine the dose-response relationship between the first pregnancy age and hypertension or blood pressure indicators. Results: of SBP, DBP, and MAP showed a trend of first increasing and then decreasing with increasing first pregnancy age and there was no statistical significance after first pregnancy age beyond 33 years on SBP, DBP, and MAP, respectively. A 1-year increment in first pregnancy age was associated with a 2.9% [OR (95% CI): 1.029 (1.010, 1.048)] higher odds of prevalent hypertension. The odds of hypertension increased sharply and then eventually leveled off with an increment of first pregnancy age after adjusting for potential confounders. Conclusion: First pregnancy age might increase the risk of hypertension later in life and might be an independent risk factor for hypertension in women

Blood pressure · Cohort · Confounding · Environmental health · Heart rate · Hypertension in Pregnancy · Logistic regression · Mean arterial pressure · Obstetrics · Odds ratio · Population · Preeclampsia · Pregnancy · Birth, Development, and Health · Gestational Diabetes Research and Management · Medicine · Pregnancy and preeclampsia studies · Internal Medicine

Tools

Open DOIOpen Access