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Global, regional, and national burden of tracheal, bronchus, and lung cancer attributable to ambient particulate matter pollution among adults aged 70 and above in 1990–2021 and projected to 2044

Bibliographic Data

ID22075305
AuthorsKe‐Jie He (0000-0001-7406-6254, Wenzhou Medical University, corresponding author), Ke-Jie He, Haitao Wang (0000-0001-9900-8528, Southwest Medical University), Jianguang Xu (0000-0002-9405-5453, Wenzhou Medical University), Guoyu Gong (Xiamen University)
Year2025
Volume13
Pages1524534-1524534
Publication date2025-01-23
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1524534
PMID39916713
OpenAlexW4406774800
LanguageEN
Citations received1
References cited43

Background: Tracheal, bronchus, and lung (TBL) cancer attributable to ambient particulate matter pollution (APMP) is a growing global health concern, particularly in individuals aged 70 and above. This study aims to evaluate past trends, identify key drivers, and project future disease burden. Methods: Data from the Global Burden of Disease Study 2021 was analyzed for TBL cancer-related disability-adjusted life years (DALYs) and mortality from 1990 to 2021, stratified by SDI regions. Statistical methods, including Joinpoint regression, age-period-cohort modeling, and decomposition analysis, were used to identify temporal trends and drivers of DALYs. Future projections were made using the Nordpred model. Results: From 1990 to 2021, global DALYs of TBL cancer due to APMP increased steadily (AAPC 0.75%). Population growth was the main driver, accounting for 79.37% of the increase, with epidemiological factors playing a varying role across regions. The highest DALY growth was observed in middle SDI regions (AAPC 2.99%), while high SDI regions saw a decline (AAPC -1.76%). Projections up to 2044 suggest a substantial increase in DALYs across all SDI regions, with the fastest growth expected among individuals aged 70-74, but DALY rates are projected to decline steadily. Conclusion: Population growth is the primary factor driving the increase in DALYs associated with TBL cancer, with significant regional disparities. Projections suggest a continued rise in disease burden, particularly in lower SDI regions, underlining the urgency for targeted public health interventions and strategies to mitigate exposure and improve healthcare outcomes for at-risk populations

Burden of disease · Disease burden · Environmental health · Environmental protection · Geography · Lung cancer · Pathology · Population · Public health · Air Quality and Health Impacts · Demography · Health, Environment, Cognitive Aging · Medicine · Occupational and environmental lung diseases · Epidemiology

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Citations per year1
Citation span2025 - 2025 (1)
Highly citedNo

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