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Socioeconomic disparities in HPV vaccine uptake

Multivariable analysis of vaccination data from Tianjin (2018–2023)

Bibliographic Data

ID22075461
AuthorsJing Xiang (0000-0003-2026-7354, Nankai University), Xuan Sun (0000-0002-7450-6210, Nankai University, corresponding author)
Year2025
Volume13
Pages1428267-1428267
Publication date2025-02-27
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1428267
PMID40084203
OpenAlexW4408005708
LanguageIT
Citations received3
References cited38

Objectives As the first socio-demographic profiling of HPV vaccines in Chinese cities, this study assesses equity implications through compositional analysis of covered populations, with multilevel examination of vaccine-type selection determinants. Method Utilizing HPV vaccination data obtained from the Jinnan Center for Disease Control and Prevention (CDC) spanning from 2018 to 2023, we conducted a retrospective analysis. Hierarchical logistic regression was employed to model the joint effects of age, ethnicity, occupation, and urban–rural residence on vaccination behaviors. Vaccine type preference was categorized as bivalent, quadrivalent, or nonavalent. Result Three key disparities were revealed in the analysis. Age-stratified access revealed the highest proportion of recipients among women aged 33–38 years (29.6%) and 39–44 years (21.9%), contrasting with less than 1% participation in the 9–14 year-old cohort. Educationally, 87.3% held at least a bachelor’s degree, compared to 12.7% with below-college education ( χ 2 = 6048.89, p < 0.001). Clear urban–rural divide, with 99.7% of recipients in urban areas and just 0.3% in rural areas ( χ 2 = 76.79, p < 0.001). Vaccine-type selection showed socioeconomic patterns, with nonavalent vaccines preferred by urban professionals (OR = 1.577, 95% CI: 1.16–2.142) and those with incomes above 5000 yuan (OR = 1.958, 95% CI: 0.26–3.527). Conclusion Demonstrating Hart’s Inverse Care Law, Tianjin’s program disproportionately immunizes socioeconomically secure urbanites. We propose: (1) school-based mandates for pre-sexual debut cohorts; (2) rural vaccination-social insurance integration; (3) domestic 9-valent vaccine development with needs-based subsidies. These evidence-based reforms are critical for achieving equitable 90% coverage by 2030

Environmental health · Population · Socioeconomic status · Vaccination · Cervical Cancer and HPV Research · Immune responses and vaccinations · Medicine · Vaccine Coverage and Hesitancy · Virology

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Unique citing works3
Citations per year3
Citation span2026 - 2026 (1)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 3

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