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Identification of Variable Importance for Predictions of Mortality From Covid-19 Using AI Models for Ontario, Canada

Bibliographic Data

ID22075844
AuthorsBrett Snider (0000-0003-4883-6045, University of Guelph, corresponding author), Edward A Mcbean (0000-0002-4701-5467, University of Guelph), John Yawney (0000-0003-4269-9537, Alberta Oil Sands Technology and Research Authority), S Andrew Gadsden (0000-0003-3749-0878, University of Guelph), Bhumi Patel (University of Guelph)
Year2021
Volume9
Pages675766-675766
Publication date2021-06-21
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2021.675766
PMID34235131
OpenAlexW3174667040
LanguageEN
References cited18

The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has challenged medical systems to the brink of collapse around the globe. In this paper, logistic regression and three other artificial intelligence models (XGBoost, Artificial Neural Network and Random Forest) are described and used to predict mortality risk of individual patients. The database is based on census data for the designated area and co-morbidities obtained using data from the Ontario Health Data Platform. The dataset consisted of more than 280,000 COVID-19 cases in Ontario for a wide-range of age groups; 0–9, 10–19, 20–29, 30–39, 40–49, 50–59, 60–69, 70–79, 80–89, and 90+. Findings resulting from using logistic regression, XGBoost, Artificial Neural Network and Random Forest, all demonstrate excellent discrimination (area under the curve for all models exceeded 0.948 with the best performance being 0.956 for an XGBoost model). Based on SHapley Additive exPlanations values, the importance of 24 variables are identified, and the findings indicated the highest importance variables are, in order of importance, age, date of test, sex, and presence/absence of chronic dementia. The findings from this study allow the identification of out-patients who are likely to deteriorate into severe cases, allowing medical professionals to make decisions on timely treatments. Furthermore, the methodology and results may be extended to other public health regions

Artificial neural network · Biology · Disease · Geography · Logistic regression · Machine learning · Pandemic · Pathology · Public health · Random forest · Statistics · Computer Science · COVID-19 Clinical Research Studies · COVID-19 diagnosis using AI · Demography · Machine Learning in Healthcare · Mathematics · Medicine · Artificial Intelligence · Internal Medicine

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