Patient subgroups and shifting incidence trends
An epidemiological profile of registered severe mental disorders in Quzhou, China (1969–2022)
Bibliographic Data
| ID | 22075958 |
|---|---|
| Authors | Lushan Wang (Taiwan Centers for Disease Control), Yuefen Wan (Third People's Hospital of Huzhou), Feipeng Chen (0000-0001-5973-5261, Taiwan Centers for Disease Control), Chunfu Fang (Taiwan Centers for Disease Control), Ruifang Zhao (0000-0002-2735-2159, Xinjiang Uygur Autonomous Region Disease Prevention and Control Center, corresponding author), Xianchen Jiang (Taiwan Centers for Disease Control, corresponding author) |
| Year | 2026 |
| Volume | 14 |
| Pages | 1783400-1783400 |
| Publication date | 2026-06-15 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2026.1783400 |
| PMID | 42375594 |
| OpenAlex | W7164865707 |
| Language | EN |
| References cited | 30 |
Background: Severe mental disorders (SMD) pose a significant public health challenge. Comprehensive epidemiological data are crucial for informing effective management strategies, yet detailed profiles from specific regions like Quzhou, China, remain limited. Methods: This retrospective study analyzed data from 11,589 patients with registered SMD in Quzhou, sourced from the National Information System for Psychosis. We extracted demographic, clinical, and management information. Statistical analyses included descriptive statistics, chi-square/Fisher's exact tests to compare characteristics across six SMD categories, hierarchical cluster analysis to explore disorder groupings, and Joinpoint regression to analyze incidence trends from 1969 to 2022. Results: < 0.001) were observed in all sociodemographic and clinical variables across disorder types. Cluster analysis identified three distinct groups: (1) schizophrenia, bipolar affective disorder, and paranoid mental disorder; (2) intellectual disability with associated psychiatric disorder (a highly distinct profile); and (3) psychiatric disorders due to epilepsy and schizoaffective disorder. Joinpoint regression indicated a significant overall increase in crude incidence from 1969 to 2022, with an Average Annual Percent Change of 6.06% (95% CI: 5.04 to 7.14%), characterized by a strong rise until 2013 with an Annual Percent Change (APC) of 8.40% (95% CI: 7.58 to 9.58%), after which the trend stabilized, showing a non-significant downward trend (APC: -4.67%; 95% CI: -26.80 to 3.24%). Conclusion: This study provides a detailed epidemiological profile of SMD in Quzhou, revealing distinct patient subgroups and a recent plateau in the incidence trend. The findings underscore the need for differentiated, cluster-informed public health planning and resource allocation to address the varied needs of this population
Bipolar disorder · Cohort · Mental health · Public health · Schizoaffective disorder · Bipolar Disorder and Treatment · Mental Health Treatment and Access · Schizophrenia research and treatment · Epidemiology
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Integrated mental health services in China
| Highly cited | No |
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