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High rate of marginal vitamin A deficiency in children aged 0–6 years in Quanzhou, China

A cross-sectional study

Bibliographic Data

ID22075972
AuthorsXiaoyan Zhou (0000-0002-4166-6787, Fujian Medical University), Xiaoyan Zhuang (Fujian Women and Children Hospital), Huiling Huang (0000-0001-5937-8022, Fujian Women and Children Hospital), Jiajia Liu (0000-0002-1923-5964, Fujian Women and Children Hospital), Qingling Zhu (0000-0003-3846-1227, Fujian Medical University, corresponding author)
Year2026
Volume14
Pages1727761-1727761
Publication date2026-03-25
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2026.1727761
PMID41960392
OpenAlexW7140285959
LanguageEN
References cited32

Objective To evaluate the vitamin A nutritional status and identify associated factors among children aged 0–6 years in Quanzhou, China, to support the development of targeted intervention strategies. Method This study included 1,183 healthy children (0–6 years) from January 2022 to March 2023. Serum retinol was measured via LC–MS/MS, and anthropometric data were collected. The vitamin A status was compared by gender, age and BMI. Results The median serum retinol concentration was 1.12 μmol/L (95% CI: 0.94–1.29). The overall prevalence of marginal deficiency or deficiency (serum retinol 0.05). Conclusion There is a concerning high prevalence of marginal vitamin A deficiency among young children in Quanzhou, representing a notable public health issue, particularly severe in infants. Interventions should be age-specific and incorporate BMI-related metabolic considerations to effectively address vitamin A insufficiency in this and similar populations

Anthropometry · Cross-sectional study · Odds ratio · Retinol · Underweight · Vitamin · Vitamin A deficiency · vitamin D deficiency · Antioxidant Activity and Oxidative Stress · Drug-Induced Ocular Toxicity · Retinoids in leukemia and cellular processes

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