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Health-state utility values and their time to deterioration in informal caregivers of older patients with chronic diseases

Bibliographic Data

ID22076192
AuthorsAstrid Pozet (0000-0003-4371-1112, Centre Hospitalier Universitaire de Besançon), Antoine Falcoz (Inserm), Cécile Roller (Centre Hospitalier Universitaire de Besançon), Taha Jai (Centre Hospitalier Universitaire de Besançon), Aurelia Meurisse (Inserm), Virginie Nerich (0000-0002-0351-6040, Inserm, corresponding author)
Year2025
Volume13
Pages1531608-1531608
Publication date2025-04-30
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1531608
PMID40371298
OpenAlexW4409980699
LanguageEN
References cited22

Objectives This study aimed to assess health state utility values (HSUVs) in caregivers of older patients with chronic diseases receiving or not receiving social worker support. Methods This multicentric open-label randomized study assigned caregivers to receive either an informational booklet alone or one accompanied by social worker support. Caregivers completed EQ-5D-3L each semester for 24 months. We reported caregiver HSUVs at baseline and after 6, 12, 18, and 24 months using EQ-5D-3L utility index scores and exploring their time to deterioration (TTD). Results Among 179 included caregivers, the percentage reporting some or extreme problems on five EQ-5D-3L dimensions remained almost stable over time with a median EQ-5D-3L utility index score of 0.89 [0.80–1.00] at baseline ( n = 177), 0.80 [0.80–0.89] at M6 ( n = 125), and 0.80 [0.73–0.91] at M24 ( n = 81). Among the respondents, 62% ( n = 109) experienced a deterioration in EQ-5D-3L utility index score, with a median TTD of 9.1 months [95%CI 6.2–14.9] in the control group (CG) and 9.5 months [6.3–14.4] in the supportive intervention group (SIG) (HR = 1.06 [0.73–1.54]), p -value = 0.76. Conclusion Our study provides a catalog of HSUVs across different caregiver profiles and at various follow-up time points, which can inform future economic evaluations. Clinical trial registration ClinicalTrials.gov , NCT02626377

Chronic disease · Intensive care medicine · State of health · Chronic Disease Management Strategies · Dialysis and Renal Disease Management · Health Systems, Economic Evaluations, Quality of Life · Medicine · Gerontology

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