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Clinical Characteristics of Patients With Re-admitted of Novel Coronavirus 2019 (nCovid-19) in Wenzhou, China

Bibliographic Data

ID22076615
AuthorsXinchun Ye (Wenzhou Central Hospital), Yuping Yuan (0009-0008-5161-5730, Wenzhou Central Hospital), Risheng Huang (0009-0004-6833-8806, Wenzhou Central Hospital), Aiqiong Cheng (Wenzhou Central Hospital), Zhijie Yu (0000-0002-4901-3545, Wenzhou Medical University), Ziyang Huang (0000-0001-6422-225X, Wenzhou Medical University), Rongrong Chen (0000-0002-4489-4179, Wenzhou Medical University), Xiangao Jiang (Wenzhou Central Hospital), Yuanliang Zheng (Wenzhou Central Hospital), Jichan Shi (0000-0001-9421-2706, Wenzhou Central Hospital, corresponding author)
Year2021
Volume9
Pages649178-649178
Publication date2021-05-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2021.649178
PMID34055717
OpenAlexW3163257216
LanguageEN
References cited9

Background: During the COVID-19 pandemic, many patients admitted to hospital for treatment have recovered and been discharged; however, in some instances, these same patients are re-admitted due to a second fever or a positive COVID-19 PCR test result. To ascertain whether it is necessary to treat these patients in hospitals, especially in asymptomatic cases, we summarize and analyze the clinical and treatment characteristics of patients re-admitted to hospital with a second COVID-19 infection. Methods: Of the 141 COVID-19 cases admitted to the Wenzhou Central Hospital between January 17, 2020, to March 5, 2020, which were followed until March 30, 2020, 12 patients were re-admitted with a second COVID-19 infection. Data was collected and analyzed from their clinical records, lab indexes, commuted tomography (CT), and treatment strategies. Results: Most of the 141 patients had positive outcomes from treatment, with only 12 (8.5%) being re-admitted. In this sub-group: one (8.3%) had a fever, a high white blood cell count (WBC), and progressive CT changes; and one (8.3%) had increased transaminase. The PCR tests of these two patients returned negative results. Another 10 patients were admitted due to a positive PCR test result, seven of which were clinically asymptomatic. Compared to the CT imaging following their initial discharge, the CT imaging of all patients was significantly improved, and none required additional oxygen or mechanical ventilation during their second course of treatment. Conclusions: The prognoses of the re-admitted patients were good with no serious cases. We conclude that home treatment with concentrated medical observation is a safe and feasible course of treatment if the patient returns a positive PCR test result but does not display serious clinical symptoms. During medical observation, patients with underlying conditions should remain a primary focus, but most do not need to be re-admitted to the hospital

Asymptomatic · Disease · Mechanical ventilation · Nucleic acid test · Pandemic · White blood cell · COVID-19 Clinical Research Studies · COVID-19 diagnosis using AI · Long-Term Effects of COVID-19 · Medicine · Emergency Medicine · Internal Medicine · Pediatrics

  • Virological assessment of hospitalized patients with Covid-2019

    Open Access•Roman Wölfel, Victor M Corman et al.•Nature•2020

  • A Novel Coronavirus from Patients with Pneumonia in China, 2019

    Na Zhu, 양승민 양승민 et al.•New England Journal of Medicine•2020

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Highly citedNo

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