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Artificial intelligence–enhanced mapping of the international classification of functioning, disability and health via a mobile app

A randomized controlled trial

Bibliographic Data

ID22078071
AuthorsZhandos Kurban (Astana Medical University), Didar Khassenov (National Center for Biotechnology, corresponding author), Zhandos Burkitbaev (National Center for Biotechnology), Sholpan Bulekbayeva (0000-0002-1415-5519, National Academy of Sciences of the Republic of Kazakhstan), Azat Chinaliyev (National Center for Biotechnology), Serik Bakhtiyar (Astana Medical University), Samat Saparbayev (0000-0002-9570-4240, Astana Medical University), Tokan Sultanaliyev, Султаналиев Т А (0000-0003-1732-9489, National Center for Biotechnology), Ulzhalgas Zhunissova (0000-0001-5255-9314, Astana Medical University), Natalia Slivkina, Nataliya Slivkina (0000-0002-8165-0114, Astana Medical University), Elena Titskaya, E V Titskaya (Tomsk Scientific Research Institute of Balneology and Physiotherapy), Luis Arias, Luis F Arias (Universidad Privada de Santa Cruz de la Sierra), Dana Aldakuatova (Astana Medical University), Gulfairus Yessenbayeva (0000-0001-7841-1801, National Center for Biotechnology), Zhanerke Ermakhan (Astana Medical University)
Year2025
Volume13
Pages1590401-1590401
Publication date2025-08-05
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1590401
PMID40837960
OpenAlexW4412998156
LanguageEN
Citations received1
References cited44

Background: Mobile health applications and artificial intelligence (AI) are increasingly utilized to streamline clinical workflows and support functional assessment. The International Classification of Functioning, Disability and Health (ICF) provides a standardized framework for evaluating patient functioning, yet AI-driven ICF mapping tools remain underexplored in routine clinical settings. Objective: This study aimed to evaluate the efficiency and accuracy of the MedQuest mobile application-featuring integrated AI-based ICF mapping-compared to traditional paper-based assessment in hospitalized patients. Methods: A parallel-group randomized controlled trial was conducted in two medical centers in Astana, Kazakhstan. A total of 185 adult inpatients (≥18 years) were randomized to either a control group using paper questionnaires or an experimental group using the MedQuest app. Both groups completed identical standardized assessments (SF-12, IPAQ, VAS, Barthel Index, MRC scale). The co-primary outcomes were (1) total questionnaire completion time and (2) agreement between AI-generated and clinician-generated ICF mappings, assessed using quadratic weighted kappa. Secondary outcomes included AI sensitivity/specificity, confusion matrix analysis, and physician usability ratings via the System Usability Scale (SUS). Results: = 0.842), with 80.6% of qualifiers matching exactly. The AI demonstrated high sensitivity and specificity for common functional domains (e.g., codes 1-2), though performance decreased for rare qualifiers. The micro-averaged sensitivity and specificity were 0.806 and 0.952, respectively. Mean SUS score among physicians was 86.8, indicating excellent usability and acceptability. Conclusion: The MedQuest mobile application significantly improved workflow efficiency and demonstrated strong concordance between AI- and clinician-assigned ICF mappings. These findings support the feasibility of integrating AI-assisted tools into routine clinical documentation. A hybrid model, combining AI automation with clinician oversight, may enhance accuracy and reduce documentation burden in time-constrained healthcare environments. Trial registration: ClinicalTrials.gov, identifier NCT07021781

Human–computer interaction · International Classification of Functioning, Disability and Health · Machine learning · Pathology · Physical therapy · Randomized controlled trial · Usability · Artificial Intelligence in Healthcare and Education · Cerebral Palsy and Movement Disorders · Computer Science · Electronic Health Records Systems · Medicine · Artificial Intelligence · Rehabilitation

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Citations per year1
Citation span2026 - 2026 (1)
Highly citedNo

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