A national cross-sectional analysis of selenium intake and risk of osteoarthritis
Nhanes 2003–2016
Bibliographic Data
| ID | 22078387 |
|---|---|
| Authors | Xiaoyu Deng (0000-0001-7802-0966, Sichuan University), Yongqiong Tan (0000-0002-5112-0518, Sichuan University, corresponding author) |
| Year | 2023 |
| Volume | 10 |
| Pages | 1047605-1047605 |
| Publication date | 2023-01-09 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2022.1047605 |
| PMID | 36699932 |
| OpenAlex | W4315490695 |
| Language | EN |
| Citations received | 1 |
| References cited | 25 |
Background The association between dietary selenium intake and arthritis, rheumatoid arthritis (RA), and osteoarthritis (OA) is inconsistent in previous studies and remain unclear. To investigate their relationship, this study was performed. Methods Data from the National Health and Nutrition Examination Survey (2003–2016) were downloaded and further analyzed. Dietary Se intake was classified according to quartiles with quartile 1 (Q1) having the lowest intake and quartile 4 (Q4) having the highest intake. Weighted logistic regression was used to investigate the association between dietary selenium intake and arthritis, RA, and OA. Subgroup analyses were performed to verify the findings. To further examine the non-linear relationship between dietary selenium intake and OA, restricted cubic spline (RCS) was adopted. Results In the crude model, the highest level of dietary selenium intake was siginificantly associated with decreased risks of arthritis (OR: 0.40, 95% CI: 0.37, 0.44) and rheumatoid arthritis (OR: 0.47, 95% CI: 0.40, 0.54), respectively. In the fully adjusted model, dietary selenium intake was not associated with risk of arthritis and RA (all P > 0.05). Conversely, the risk of OA was noted for participants with higher selenium intake (odds ratio of quartile 4 = 1.33, 95% CI = 1.07–1.65, P 0.05). Conclusion Using data from NHANES, this study discloses that high dietary selenium intake might be associated with risk of OA. However, the generalization of conclusion needs further examination because of the limitation of dietary questionnaire survey
Arthritis · Confidence interval · Cross-sectional study · Diabetes mellitus · Environmental health · Logistic regression · National Health and Nutrition Examination Survey · Odds ratio · Osteoarthritis · Pathology · Population · Quartile · Rheumatoid arthritis · Selenium · Medicine · Nutritional Studies and Diet · Selenium in Biological Systems · Therapeutic Uses of Natural Elements · Endocrinology · Internal Medicine
| Unique citing works | 1 |
|---|---|
| Citations per year | 0.5 |
| Citation span | 2024 - 2024 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |