Anticipating Unipolar Depression and Bipolar Depression in young adult with first episode of depression using childhood trauma and personality

Bibliographic Data

ID22078556
AuthorsJiali Liu (0009-0004-7210-958X, Central South University), Yuanyuan Wang (0000-0001-8181-3465), Yuan Yuan Wang (0000-0002-2141-4056, De Montfort University), Amanda Wilson (0000-0003-1384-0394, De Montfort University), Hui Chen (0000-0003-2866-7811, Central South University), Peiqu Liu (Central South University), Xianliang Chen (0000-0001-9007-4924, Central South University), Huajia Tang (Central South University), Chenyuli Luo (Dongguan People’s Hospital), Yusheng Tian (0009-0003-9805-361X, Central South University), Xiaoping Wang (0000-0002-7862-0491, Central South University), Xia Cao (0000-0002-1133-5266, Central South University, corresponding author), Jiansong Zhou (0000-0002-4410-4202, Central South University, corresponding author)
Year2023
Volume10
Pages1061894-1061894
Publication date2023-01-10
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.1061894
PMID36703813
OpenAlexW4315433955
LanguageEN
Citations received4
References cited38

Objective Relevant research focusing on young adults with Unipolar Depression (UD) and Bipolar Depression (BD) is limited. The current research aims to investigate childhood trauma and personality traits in young adults with UD and BD. Methods Two hundred and thirty-five patients in a first depressive episode (diagnosed UD and BD), 16–25 years old, were recruited from Second Xiangya Hospital. And 79 healthy controls (HC) were recruited from the community to form the comparison group. Patients' childhood trauma was measured by the Childhood Trauma Questionnaire (CTQ), and personality was measured by Eysenck Personality Inventory (EPI). The Kruskal-Wallis test was used to compare depression, anxiety, CTQ, and EPI scores between the HC ( n = 79), UD ( n = 131), and BD ( n = 104) groups. Factors independently associated with mood disorders and BD were determined using binary logistic regression analyses. Results Compared with HC, mood disorders had more severe anxiety and depression symptoms, and higher CTQ. Emotional abuse (OR = 1.47; 95% CI = 1.08–2.01), emotional neglect (OR = 1.24; 95% CI = 1.05–1.46), and neuroticism (OR = 1.25; 95% CI = 1.16–1.35) were associated with significantly increased odds of mood disorders. Whereas, higher extraversion scores were a protective factor for mood disorders. Compared with UD, BD had more severe anxiety symptoms, and higher CTQ, than extraversion and neuroticism personality scores. Anxiety (OR = 1.06; 95% CI = 1.02–1.08) and extraversion (OR = 1.05; 95% CI = 1.03–1.09) were associated with significantly increased odds of BD. Conclusion Interventions to prevent childhood trauma may improve young adults' mental health. Using childhood trauma and personality to anticipate BD and UD creates more accurate treatment for young adults with first depression

Personality · Psychiatry · Psychoanalysis · Bipolar Disorder and Treatment · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Medicine · Psychology · Tryptophan and brain disorders

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