Time to viral load suppression and its predictors among people living with HIV on antiretroviral therapy in Gebi Resu zone, Afar Region, Ethiopia, 2023
Bibliographic Data
| ID | 22078734 |
|---|---|
| Authors | Anteneh Tefera Chirnet (Adama Science and Technology University, corresponding author), Ephrem Mannekulih Habtewold (0000-0003-0178-7119, Adama Science and Technology University), Haji Aman, Haji Aman Deybasso (0000-0003-1441-3300, Adama Science and Technology University), Elias Bekele Wakwoya (0000-0001-5520-4308, Asossa University), Sewnet Getaye Workie (0000-0002-2676-6958, Debre Berhan University) |
| Year | 2024 |
| Volume | 12 |
| Pages | 1384787-1384787 |
| Publication date | 2024-10-28 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2024.1384787 |
| PMID | 39529713 |
| OpenAlex | W4403806602 |
| Language | EN |
| References cited | 33 |
Objective: This study aimed to estimate the time to viral load suppression and identify its predictors among HIV patients receiving antiretroviral therapy (ART) in the Gebi Resu zone, Afar Region, Ethiopia, 2023. Setting: The study was conducted at public health facilities in the Gebi Resu zone of the Afar region. Study design: This study is a facility-based, retrospective follow-up study. Study participants: This study included 298 people living with HIV who were receiving ART services at selected health facilities in the Gebi Resu zone. Data were collected by reviewing patient records using a structured checklist. Bivariate and multivariate Cox regression analyses were conducted to assess the relationship between variables and control for confounders. Results: The incidence rate of viral load suppression was 9.46 per 100 person-months. The median time to viral load suppression was 7.7 months, with an interquartile range of 3.8 months (IQR = 6.47-10.27). Patients at clinical stages 3 and 4 [AHR = 0.67, 95%CI (0.47, 0.96)], those who received cotrimoxazole prophylaxis therapy [AHR = 1.47, 95%CI (1.12, 1.92)], and patients with poor drug adherence [AHR = 0.40, 95%CI (0.18, 0.90)] were significantly associated with time to viral load suppression among people on antiretroviral therapy. Conclusion: The time to viral load suppression and the median time to viral load suppression among people living with HIV on ART were shorter than those observed in many developing and developed countries. Clinical stage, cotrimoxazole prophylaxis therapy, and drug adherence were significant predictors of viral load suppression
Antiretroviral therapy · Checklist · Confounding · Interquartile range · Multivariate analysis · Retrospective cohort study · Viral load · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Pneumocystis jirovecii pneumonia detection and treatment · Immunology · Internal Medicine
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection
Human Immunodeficiency Virus Transmission at Each Step of the Care Continuum in the United States
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Sociodemographic factors affecting viral load suppression among people living with HIV in South Carolina
Hunger, waiting time and transport costs
The WHO Clinical Staging System for HIV/Aids
| Citation velocity | historical |
|---|---|
| Highly cited | No |