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A study on the construction of a model for sustained ICS medication adherence behavior in children with asthma

Bibliographic Data

ID22079454
AuthorsYan Li (0000-0001-6650-7726, Children's Hospital of Chongqing Medical University), Li Yan (0000-0002-5258-8649), Rong Guo (0000-0002-0807-1490, Children's Hospital of Chongqing Medical University, corresponding author), Liping Wu (0000-0003-2803-3253, Children's Hospital of Chongqing Medical University), Chunlan Yin (Children's Hospital of Chongqing Medical University), Jianlan Tang (Children's Hospital of Chongqing Medical University)
Year2025
Volume13
Pages1590423-1590423
Publication date2025-09-29
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1590423
PMID41089876
OpenAlexW4414608152
LanguageEN
References cited32

Objective To develop a Sustained Adherence Behavior Model for inhaled corticosteroids (ICS) Medication in Children with Asthma. Method Through literature review and semi-structured interviews, a questionnaire item pool was developed to assess the factors influencing the medication adherence behavior of asthma children using ICS. Expert consultation was conducted, involving two rounds of inquiries with experts, ultimately resulting in the development of the influence factors scale. The scale, along with the general situation survey of asthma children and the bronchial asthma medication adherence scale, was used to survey 370 asthma children who visited the outpatient department. Finally, a model of ICS medication adherence behavior for asthma children was established. Results The positive coefficients of the two rounds of expert consultation were 90.5% and 95.2%, and the Kendall concordance coefficients were 0.384 and 0.278 (both P < 0.01). The Cronbach's α coefficient of the questionnaire was 0.925. The final asthma children's ICS medication adherence behavior influence factors scale consisted of 5 first-level items and 23 second-level items. Structural equation modeling analysis showed that the direct effects on medication adherence were behavioral intention (0.522), medication knowledge (0.193), and medication belief (0.181). The indirect effects were normative belief (0.161) and self-efficacy (0.140). The coefficient of determination ( R 2 ) for the influencing factors was 0.46 ( P < 0.01). Conclusion The behavioral model based on the Health Belief Theory effectively analyzes the factors influencing the ICS medication adherence behavior of asthma children, with the greatest impact coming from behavioral intention, followed by medication belief and medication knowledge

Asthma · Asthma medication · Health behavior · Health belief model · Medication adherence · Patient compliance · Theory of planned behavior · Asthma and respiratory diseases · Medication Adherence and Compliance · Mobile Health and mHealth Applications

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