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Radiation therapy for prostate cancer in Syrian refugees

Facing the need for change

Bibliographic Data

ID22079474
AuthorsMehmet Fuat Eren (0000-0002-6531-978X, Marmara University), Sarah S Kılıç (0000-0002-4015-2901, Cleveland Clinic), Sarah S Kilic, Ayfer Ay Eren (0000-0003-0641-3378, Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi), Sedenay Oskeroglu Kaplan (Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi), Fatma Teke (0000-0001-7990-3509, Dicle University), Tugce Kutuk (0000-0003-0416-8612, Malatya Devlet Hastanesi), Beyhan Ceylaner Bicakci, Beyhan Ceylaner Bıçakçı (0000-0003-2509-6742, Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi), Lara Hathout (0000-0003-3062-9793, Rutgers, the State University of New Jersey), Shalini Moningi (0000-0003-2638-8202, Brigham and Women's Hospital), Peter Orio, Peter F Orio (0000-0002-0594-4727, Brigham and Women's Hospital), Banu Atalar (0000-0001-8435-8074, Acıbadem University), Mutlay Sayan (0000-0002-0101-0951, Brigham and Women's Hospital, corresponding author)
Year2023
Volume11
Pages1172864-1172864
Publication date2023-05-31
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1172864
PMID37325331
OpenAlexW4378901985
LanguageEN
Citations received1
References cited25

Purpose To report the utilization of radiation therapy in Syrian refugee patients with prostate cancer residing in Turkey. Methods and materials A multi-institutional retrospective review including 14 cancer centers in Turkey was conducted to include 137 Syrian refugee patients with prostate cancer treated with radiation therapy (RT). Toxicity data was scored using the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0. Noncompliance was defined as a patient missing two or more scheduled RT appointments. Results Advanced disease, defined as stage III or IV, was reported in 64.2% of patients while androgen deprivation therapy (ADT) was only administrated to 20% of patients. Conventionally fractionated RT with a median number of 44 fractions was delivered to all patients with curative intent ( n = 61) while palliative RT ( n = 76) was delivered with a median number of 10 fractions. The acute grade 3–4 toxicity rate for the entire cohort was 16%. Noncompliance rate was 42%. Conclusion Most Syrian refugee prostate cancer patients presented with advanced disease however ADT was seldom used. Despite the low treatment compliance rate, conventional fractionation was used in all patients. Interventions are critically needed to improve screening and increase the use of standard-of-care treatment paradigms, including hypofractionated RT and ADT

Androgen deprivation therapy · Cancer · Cohort · Common Terminology Criteria for Adverse Events · Prostate cancer · Radiation therapy · Advances in Oncology and Radiotherapy · Management of metastatic bone disease · Medicine · Prostate Cancer Diagnosis and Treatment · Internal Medicine

  • Global burden of cancer among refugees

    Open Access•Fantu Mamo Aragaw, Angela Dawson et al.•Journal of Migration and Health•2025

  • Communicable diseases in complex emergencies

    Open Access•Máire A Connolly, Michelle Gayer et al.•The Lancet•2004

Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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