Forging the path to precision medicine in Qatar
A public health perspective on pharmacogenomics initiatives
Bibliographic Data
| ID | 22079923 |
|---|---|
| Authors | Kholoud Bastaki (0000-0003-2646-1123, Qatar University, corresponding author), Dinesh Velayutham (0000-0002-9425-7266, Hamad bin Khalifa University), Areeba Irfan (Hamad bin Khalifa University), Mohd Adnan (0000-0002-7080-6822, Hamad bin Khalifa University), Sawsan Mohammed (0000-0002-7836-4352, Qatar University), Hamdi Mbarek (0000-0002-1108-0371, Qatar Airways (Qatar)), M Waild Qoronfleh, Puthen V Jithesh (0000-0001-7747-0930, Hamad bin Khalifa University, corresponding author) |
| Year | 2024 |
| Volume | 12 |
| Pages | 1364221-1364221 |
| Publication date | 2024-03-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2024.1364221 |
| PMID | 38550311 |
| OpenAlex | W4392797927 |
| Language | EN |
| References cited | 67 |
Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate PGx test into clinical setting, identifying the potential barriers and challenges as well as planning the future directions, are all important for fruitful PGx implementation in any population. Qatar serves as an exemplar case study for the Middle East, having a small native population compared to a diverse immigrant population, advanced healthcare system, national genome program, and several educational initiatives on PGx and precision medicine. This paper attempts to outline the current state of PGx research and implementation in Qatar within the global context, emphasizing ongoing initiatives and educational efforts. The inclusion of PGx in university curricula and healthcare provider training, alongside precision medicine conferences, showcase Qatar’s commitment to advancing this field. However, challenges persist, including the requirement for population specific implementation strategies, complex genetic data interpretation, lack of standardization, and limited awareness. The review suggests policy development for future directions in continued research investment, conducting clinical trials for the feasibility of PGx implementation, ethical considerations, technological advancements, and global collaborations to overcome these barriers
Bioinformatics · Data science · Engineering ethics · Environmental health · Geography · Health care · Pathology · Personalized medicine · Pharmacogenomics · Political science · Population · Precision medicine · Standardization · Berberine and alkaloids research · Biosimilars and Bioanalytical Methods · Computer Science · Engineering · Medicine · Pharmacogenetics and Drug Metabolism · Psychology
| Highly cited | No |
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