Association between PM2.5-bound metals and pediatric respiratory health in Guangzhou

An ecological study investigating source, health risk, and effect

Bibliographic Data

ID22080306
AuthorsYi Zheng (0000-0002-2228-2948, Guangzhou Medical University), Sili Chen (Guangzhou Medical University), Yuyang Chen (0000-0002-5220-0501, Southern Medical University), Jingye Li (0000-0001-6561-2962, Guangzhou Medical University), Binhe Xu (Zunyi Medical University), Tongxing Shi (0000-0002-2528-9379, Guangzhou Center for Disease Control and Prevention), Qiaoyuan Yang (Guangzhou Medical University, corresponding author)
Year2023
Volume11
Pages1137933-1137933
Publication date2023-03-09
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1137933
PMID36969623
OpenAlexW4323665933
LanguageEN
Citations received2
References cited36

Background The adverse effects of 2.5-μm particulate matter (PM 2.5 ) exposure on public health have become an increasing concern worldwide. However, epidemiological findings on the effects of PM 2.5 -bound metals on children's respiratory health are limited and inconsistent because PM 2.5 is a complicated mixture. Objectives Given the vulnerability of children's respiratory system, aim to pediatric respiratory health, this study evaluated the potential sources, health risks, and acute health effects of ambient PM 2.5 -bound metals among children in Guangzhou, China from January 2017 to December 2019. Methods Potential sources of PM 2.5 -bound metals were detected using positive matrix factorization (PMF). A health risk assessment was conducted to investigate the inhalation risk of PM 2.5 -bound metals in children. The associations between PM 2.5 -bound metals and pediatric respiratory outpatient visits were examined with a quasi-Poisson generalized additive model (GAM). Results During 2017–2019, the daily mean concentrations of PM 2.5 was 53.39 μg/m 3 , and the daily mean concentrations of PM 2.5 -bound metals range 0.03 ng/m 3 [thorium (Th) and beryllium (Be)] from to 396.40 ng/m 3 [iron (Fe)]. PM 2.5 -bound metals were mainly contributed by motor vehicles and street dust. PM 2.5 -bound arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr)(VI), nickel (Ni), and lead (Pb) were found to pose a carcinogenic risk (CR). A quasi-Poisson GAM was constructed that showed there were significant associations between PM 2.5 concentrations and pediatric outpatient visits for respiratory diseases. PM 2.5 was significantly associated with pediatric outpatient visits for respiratory diseases. Moreover, with a 10 μg/m 3 increase in Ni, Cr(VI), Ni, and As concentrations, the corresponding pediatric outpatient visits for respiratory diseases increased by 2.89% (95% CI : 2.28–3.50%), acute upper respiratory infections (AURIs) increased by 2.74% (2.13–3.35%), influenza and pneumonia (FLU&PN) increased by 23.36% (20.09–26.72%), and acute lower respiratory infections (ALRIs) increased by 16.86% (15.16–18.60%), respectively. Conclusions Our findings showed that PM 2.5 and PM 2.5 -bound As, Cd, Co, Cr(VI), Ni, and Pb had adverse effects on pediatric respiratory health during the study period. New strategies are required to decrease the production of PM 2.5 and PM 2.5 -bound metals by motor vehicles and to reduce levels of street dust to reduce children's exposure to these pollutants and thereby increase child health

Environmental health · Air Quality and Health Impacts · Climate Change and Health Impacts · Medicine · Noise Effects and Management · Psychology

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