Global, regional, and national burden of 10 digestive diseases in 204 countries and territories from 1990 to 2019

Bibliographic Data

ID22081076
AuthorsRui Wang (0000-0001-7155-3356, Central South University), Zhaoqi Li (0000-0002-3748-8914, Central South University), Shaojun Liu (0000-0002-3311-1343, Central South University), Decai Zhang (0000-0002-0099-5664, Central South University, corresponding author)
Year2023
Volume11
Pages1061453-1061453
Publication date2023-03-28
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1061453
PMID37056655
OpenAlexW4361221098
LanguageEN
Citations received4
References cited39

Background: Digestive diseases are very common worldwide and account for considerable health care use and expenditures. However, there are no global population-based estimates of the disease burden and temporal trend of digestive diseases. Methods: Annual case numbers, age-standardized rates of prevalence, incidence, death, and disability-adjusted life-years (DALYs), and their estimated annual percentage changes (EAPCs) for digestive diseases between 1990 and 2019 were derived from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019. The association between digestive disease burden and the sociodemographic index (SDI) was investigated. We also calculated DALYs attributable to risk factors that had evidence of causation with digestive diseases. Results: Globally, in 2019, there were 88.99 million DALYs due to digestive diseases (3.51% of global DALYs). Digestive diseases were the 13th leading cause of DALYs globally in 2019. Global digestive disease DALYs were highest in the middle SDI quintile and in South Asia and were higher in males than females in 2019. Cirrhosis and other chronic liver diseases constituted the highest proportion of categorized digestive disease DALY burdens globally. From 1990 to 2019, the global age-standardized DALY rate of digestive diseases decreased from 1570.35 in 1990 to 1096.99 in 2019 per 1,00,000 population, with the EAPC being -1.32 (95% confidence interval [CI] -1.36 to -1.27). In 2019, the largest contributor to digestive disease DALYs at the global level, for both sexes, was alcohol use. Conclusion: The results of this systematic analysis suggest that the global burden of digestive diseases is substantial and varies markedly according to age, sex, SDI, and geographical region. These results provide comprehensive and comparable estimates that can potentially inform efforts toward digestive disease control worldwide

Burden of disease · Disease · Disease burden · Environmental health · Pathology · Population · Public health · Child Nutrition and Water Access · Demography · Dental Health and Care Utilization · Iron Metabolism and Disorders · Medicine · Epidemiology

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